Summary
Pseudomembranous enterocolitis is an iatrogenic illness resulting from the oral or intramuscular use of broad-spectrum antibiotics. It is characterized by diarrhea, mucosal inflammation, and pseudomembrane formation in the gastrointestinal tract. The diagnosis is established by an index of suspicion in individuals who have been on antibiotic therapy, proctosigmoido-scopic examination, stool smears, cultures, and sensitivity. Treatment should be directed to eliminating the etiologic factor and replacing the physiologic abnormality.
Similar content being viewed by others
References
Brown CH, Ferrante WA, Davis WD Jr: Toxic dilatation of the colon complicating pseudomembranous enterocolitis. Am J Dig Dis 13: 813, 1968
Craig TV: Pseudomembranous enterocolitis. Am J Surg 102: 112, 1961
Ecker JA, Williams RG, McKittrick JE, et al: Pseudomembranous enterocolitis—an unwelcome gastrointestinal complication of antibiotic therapy. Am J Gastroenterol 54: 214, 1970
Pearce C, Dineen P: A study of pseudomem-branous enterocolitis. Am J Surg 99: 292, 1960
Scott AJ, Nicholson GI, Kerr AR: Lincomycin as a cause of pseudomembranous colitis. Lancet 2: 1232, 1973
Turnbull RB Jr, Weakley FL: Atlas of Intestinal Stomas. St. Louis, C. V. Mosby, 1967 p 153
Wilder WM, Slagle GW: “The antibiotic bowel.” Med Times 96: 426, 1968
Author information
Authors and Affiliations
Additional information
Read at the meeting of the American Society of Colon and Rectal Surgeons, San Francisco, California, May 4 to 8, 1975.
About this article
Cite this article
Slagle, G.W., Boggs, H.W. Drug-induced pseudomembranous enterocolitis: A new etiologic agent. Dis Colon Rectum 19, 253–255 (1976). https://doi.org/10.1007/BF02590914
Issue Date:
DOI: https://doi.org/10.1007/BF02590914