Skip to main content

Advertisement

Log in

Drug-induced pseudomembranous enterocolitis: A new etiologic agent

  • Published:
Diseases of the Colon & Rectum

Summary

Pseudomembranous enterocolitis is an iatrogenic illness resulting from the oral or intramuscular use of broad-spectrum antibiotics. It is characterized by diarrhea, mucosal inflammation, and pseudomembrane formation in the gastrointestinal tract. The diagnosis is established by an index of suspicion in individuals who have been on antibiotic therapy, proctosigmoido-scopic examination, stool smears, cultures, and sensitivity. Treatment should be directed to eliminating the etiologic factor and replacing the physiologic abnormality.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Brown CH, Ferrante WA, Davis WD Jr: Toxic dilatation of the colon complicating pseudomembranous enterocolitis. Am J Dig Dis 13: 813, 1968

    Article  PubMed  CAS  Google Scholar 

  2. Craig TV: Pseudomembranous enterocolitis. Am J Surg 102: 112, 1961

    Article  PubMed  CAS  Google Scholar 

  3. Ecker JA, Williams RG, McKittrick JE, et al: Pseudomembranous enterocolitis—an unwelcome gastrointestinal complication of antibiotic therapy. Am J Gastroenterol 54: 214, 1970

    PubMed  CAS  Google Scholar 

  4. Pearce C, Dineen P: A study of pseudomem-branous enterocolitis. Am J Surg 99: 292, 1960

    Article  PubMed  CAS  Google Scholar 

  5. Scott AJ, Nicholson GI, Kerr AR: Lincomycin as a cause of pseudomembranous colitis. Lancet 2: 1232, 1973

    Article  PubMed  CAS  Google Scholar 

  6. Turnbull RB Jr, Weakley FL: Atlas of Intestinal Stomas. St. Louis, C. V. Mosby, 1967 p 153

    Google Scholar 

  7. Wilder WM, Slagle GW: “The antibiotic bowel.” Med Times 96: 426, 1968

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Read at the meeting of the American Society of Colon and Rectal Surgeons, San Francisco, California, May 4 to 8, 1975.

About this article

Cite this article

Slagle, G.W., Boggs, H.W. Drug-induced pseudomembranous enterocolitis: A new etiologic agent. Dis Colon Rectum 19, 253–255 (1976). https://doi.org/10.1007/BF02590914

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02590914

Keywords

Navigation