Skip to main content

Advertisement

SpringerLink
Log in

MRT-Ergebnisse bei experimentellen Muskelverletzungen

MRI results after a 2-month period of examinations on experimental injuries on rabbit muscles

  • Originalarbeiten
  • Published:
Unfallchirurgie Aims and scope Submit manuscript

Zusammenfassung

An 18 Kaninchen wurde eine Stichinzision von definierter Größe am Musculus supraspinatus vorgenommen und das kernspintomographische Signalverhalten dieses Muskels bis zum 64. Tag nach Läsion bestimmt. Während bei der Betrachtung der MRT-Bilder keine Auffälligkeiten zu erkennen waren, konnte eine charakteristische Verlaufskurve der kalkulierten T2-Zeiten (ein rechnerisches Verfahren der MRT-Software) beobachtet werden. Die kernspintomographischen Ergebnisse sind mit den histopathologischen Vorgängen nach Muskelverletzung vereinbar. Die kernspintomographische Untersuchung ermöglicht durch den Nachweis von Flüssigkeitsverschiebungen mittels kalkulierter T2-Zeiten die Beurteilung von Schäden der Muskulatur auch nach Minimalverletzungen.

Abstract

We performed an incision of standardized size and location on the suprascapularic muscle of 18 rabbits by a stab with a scalpel and measured the signal intensity of the muscle 2, 5, 11, 21, 35 and 64 days after injury (3 rabbits on each day). We did not find any detectable changes in the MRI pictures but a characteristical graph of the calculated T2-times (a mathematical procedure of the MRI software). The MRI changes correlate with the histopathological changes after muscle injury. The MRI method allows the evaluation of minor muscle trauma by the detection of a changed liquid content by using calculated T2 times.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Armstrong, R. W.: Muscle damage and endurance events. Sports Med. 3 (1986), 370–381.

    PubMed  CAS  Google Scholar 

  2. Cameron, I. L., V. A. Ord, G. D. Fullerton: Characterization of proton MRT relaxation times in normal and pathological tissues by correlation with other tissue parameters. Magnet. reson. imag. 2 (1984), 97–106.

    Article  CAS  Google Scholar 

  3. Carlson, B. M.: The regeneration of skeletal muscle: a review. Amer. J. Anat. 137 (1983), 119–150.

    Article  Google Scholar 

  4. Carlson, B. M., J. A. Faulkner: The regeneration of skeletal muscle fibres following injury: a review. Med. Sci. Sport Exerc. 15 (1983), 187–198.

    Article  CAS  Google Scholar 

  5. Clifford, J., B. A. Pethica, E. G. Smith: A nuclear magnetic resonance investigation of molecular motion in erythrocyte membranes. In: Bolis, L., B. A. Pethica (eds.): Membrane models and the formation of biological membranes. North Holland Publ., Amsterdam 1968, p. 19–42.

    Google Scholar 

  6. Fisher, B. D., V. E. Baracos, T. K. Shnitka, S. W. Mendryk, D. C. Reid: Ultrastructural events following acute muscle trauma. Med. Sci. Sports Exerc. 22 (1990), 185–193.

    PubMed  CAS  Google Scholar 

  7. Foster, A. H., B. M. Carlson: Myotoxicity of local anaesthetics and regeneration of the damaged muscle fibres. Anaesthesiol. Analg. 58 (1980), 727–736.

    Google Scholar 

  8. Fritz, V. K., W. T. Stauber: Characterization of muscle injured by forced lengthening. II. Proteoglycans. Medical Sci. Sport Exerc. 20 (1988), 354–361.

    Article  CAS  Google Scholar 

  9. Fullerton, G. D.: Physiologic basic of magnetic relaxation. In: Starck, D. D., W. G. Bradley: Magnetic resonance imaging. Mosby Comp., St. Louis 1988.

    Google Scholar 

  10. Hazlewood, C. F., D. C. Chang, B. L. Nichols, D. E. Woessner: Nuclear magnetic resonance transverse relaxation times of water protons in skeletal muscle. Biophys. J. 14 (1974), 583–606.

    Article  PubMed  CAS  Google Scholar 

  11. Hurme, T., H. Kalimo, M. Lehto, M. Järvinnen: Healing of skeletal muscle injury: an ultrastructural and immunohistochemical study. Med. Sci. Sports Exerc. 23 (1991), 801–810.

    PubMed  CAS  Google Scholar 

  12. Järvinen, M. J., T. Sorvari: Healing of a crush injury in a red striated muscle. 1. Describtion and testing of a new method of inducing a standard injury to the calf muscles. Acta path. microbiol. scand., Sect. A 83 (1975), 259.

    Google Scholar 

  13. Järvinen, M. J., T. Sorvari: Healing of a crush injury in a red straited muscle. 2. A histological study of the effect of early mobilisation/immobilisation on the repair process. Acta pathol. microbiol. scand., Sect. A 83 (1975), 269–282.

    Google Scholar 

  14. Kiricuta, I. C., V. Simplaceanu: Tissue water content and nuclear magnetic resonance in normal and tumor tissues. Cancer Res. 35 (1975), 1164–1167.

    PubMed  Google Scholar 

  15. Lehto, M. U. K., M. J. Jarvinen, O. Nelimarkka: Scar formation after skeletal muscle injury: histological and autoradiographical study in rats. Arch. orthop. Trauma Surg. 104 (1986), 366–370.

    Article  PubMed  CAS  Google Scholar 

  16. Lehto, M. U. K., M. J. Jarvinen: Muscle injuries, their healing process and treatment. Ann. chir. gynaec. 80 (1991), 102–108.

    CAS  Google Scholar 

  17. Nicholau, P. K., B. L. MacDonald, R. R. Glisson, A. V. Seaber, W. E. Garrett: Biochemical and histological evaluation of muscle after controlled strain injury. Amer. J. Sports Med. 15 (1987), 9.

    Google Scholar 

  18. Schröder, J. M.: Pathologie der Muskulatur. In: Doerr, W., G. Seifert (Hrsg.): Spezielle pathologische Anatomie, Bd. 15. Springer, Berlin 1987.

    Google Scholar 

  19. Sievers, K. W., J. Gauger, T. Bauermann, E. Löhr: Changes of soft-tissue water examined with magnetic resonance and electrical impedance tomography: an in vivo experiment. Angiology 44 (1993), 889–895.

    Article  PubMed  CAS  Google Scholar 

  20. Stauber, W. T., V. K. Fritz, D. W. Vogelbach, B. Dahlmann: Characterization of muscle injured by forced lengthening. I. Cellular infiltrates. Med. Sci. Sport Exerc. 20 (1988), 345–353.

    Article  CAS  Google Scholar 

  21. Stauber, W. T., V. K. Fritz, B. Dahlmann: Extracellular matrix changes following blcunt trauma to rat skeletal muscles. Exp. molec. Path. 52 (1990), 69–86.

    Article  PubMed  CAS  Google Scholar 

  22. Wehrli, F. W.: Principles of magnetic resonance. In: Stark, D. D., W. G. Bradley (eds.): Magnetic resonance imaging. Mosby, St. Louis 1988, p. 3–23.

    Google Scholar 

Download references

Author information

Author notes

  1. K. Küllmer

    Present address: Orthopädische Universitätsklinik, Langenbeckstraße 1, D-55101, Mainz

Authors and Affiliations

  1. Abteilung für Unfallchirurgie, Universitätsklinikum GHS Essen, Essen

    K. Küllmer, H. -J. Kock & K. P. Schmit-Neuerburg

  2. Orthopädische Klinik, Justus-Liebig-Universität Gießen, Gießen, Deutschland

    U. Harland

  3. Röntgendiagnostisches Zentralinstitut, Universitätsklinikum GHS Essen, Essen, Deutschland

    K. W. Sievers

Authors
  1. K. Küllmer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. U. Harland
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. W. Sievers
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. -J. Kock
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. K. P. Schmit-Neuerburg
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Küllmer, K., Harland, U., Sievers, K.W. et al. MRT-Ergebnisse bei experimentellen Muskelverletzungen. Unfallchirurgie 21, 59–63 (1995). https://doi.org/10.1007/BF02588731

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02588731

Search

Navigation