Skip to main content

Advertisement

Log in

Irradiation and surgery for primarily inoperable rectal adenocarcinoma

  • Published:
Diseases of the Colon & Rectum

Abstract

Preoperative irradiation followed by radical surgical removal of the tumor should be attempted in all patients with locally advanced rectal adenocarcinomas, including patients with moderate distant metastases. If the tumor is not operable after half dose of irradiation (3150 rads), the patients should be re-explored for resectability after full irrdiation dose. Resectability can only be adequately determined by exploratory laparotomy and an attempt to resect the tumor-bearing segment by anatomic dissection, and not solely by rectal exploration or palpation of the pelvis at laparotomy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Gérard A. Carcinoma of the colon and rectum: prognostic factors and criteria of responses. In: Staquet MJ, ed. Cancer therapy: prognostic factors and criteria of response; a monograph of the European organization for research on treatment of cancer. New York: Raven Press, 1975: 199–227.

    Google Scholar 

  2. Morgan CN. Treatment of the cancer of the rectum. Am J Surg 1968; 115: 442–8.

    Article  PubMed  CAS  Google Scholar 

  3. Daland EM, Welch CE, Nathanson I. One hundred untreated cancers of the rectum. N Engl J Med 1936; 214: 451–8.

    Article  Google Scholar 

  4. Stearns MW Jr, Binkley GE. Palliative surgery for cancer of the rectum and colon. Cancer 1954: 7: 1016–19.

    Article  PubMed  Google Scholar 

  5. Kligerman MM. Preoperative radiation therapy in rectal cancer. Cancer 1975; 36: 691–5.

    Article  PubMed  CAS  Google Scholar 

  6. Modlin J, Walker HS. Palliative resections in cancer of the colon and rectum. Cancer 12: 767–76.

  7. Murphy WT, Castro L: Irradiation of cancer of the rectum and rectosigmoid. Dis Colon Rectum 1964; 7: 102–5.

    PubMed  CAS  Google Scholar 

  8. Nielsen J, Balslev I, Jensen HE. Carcinoma of the colon with liver metastases: operative indications and prognosis. Acta Chir Scand 1971: 137: 463–5.

    PubMed  CAS  Google Scholar 

  9. Sterns MW Jr, Leaming RH. Irradiation in inoperable cancer. JAMA 1975; 231: 1388.

    Article  Google Scholar 

  10. Sugarbaker EV, Ketcham AS, Zubrod GF. Interdisciplinary cancer therapy: adjuvant therapy. Curr Probl Surg 1977 June 14: 58–60.

    Article  Google Scholar 

  11. Dahl O, Bjerkeset T. Stralebehandling ved adenocarcinomer i rectum og colon. Tidsskr Nor Laegeforen 1979; 28: 1383–4.

    Google Scholar 

  12. Urdaneta-Lafee N, Kligerman MM, Knowlton AH. Evaluation of palliative irradaition in rectal carcinoma. Radiology 1972; 104: 673–7.

    PubMed  CAS  Google Scholar 

  13. Wang CC, Schulz MD. The role of radiation therapy in the management of carcinoma of the sigmoid, rectosigmoid, and rectum. Radiology 1962; 79: 1–5.

    PubMed  CAS  Google Scholar 

  14. Williams IG, Horwitz H. The primary treatment of adenocarcinoma of the rectum by high voltage roentgen rays (1,000 KV.). AJR 1956; 76: 919–28.

    Google Scholar 

  15. Allen CV, Fletcher WS, Observations on preoperative irradiation of rectosigmoid carcinoma. AJR 1970; 108: 136–40.

    CAS  Google Scholar 

  16. Kligerman MM, Urdaneta-Lafee N. Observation on fifteen inoperable/nonresectable cases of rectal cancer given preoperative irradiation. AJR 1974; 120: 624–6.

    CAS  Google Scholar 

  17. Stevens KR Jr, Allen CV, Fletcher WS. Preoperative radiotherapy for adenocarcinoma of the rectosigmoid. Cancer 1976; 37: 2866–74.

    Article  PubMed  Google Scholar 

  18. Moossa AR, Ree PC, Marks JE, Levin B, Platz CE, Skinner DB. Factors influencing local recurrence after abdominoperineal resection for cancer of the rectum and rectosigmoid. Br J Surg 1975; 62: 727–30.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

About this article

Cite this article

Bjerkeset, T., Dahl, O. Irradiation and surgery for primarily inoperable rectal adenocarcinoma. Dis Colon Rectum 23, 298–303 (1980). https://doi.org/10.1007/BF02586831

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02586831

Key words

Navigation