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Gardner's syndrome with duodenal adenomas, gastric adenomyoma and thyroid papillary—Follicular adenocarcinoma

  • Published:
Diseases of the Colon & Rectum

Summary

A case of a woman with Gardner's syndrome, originally manifested by multiple adenomatous polyps of the colon, is presented. She underwent subtotal colectomy at 14 years of age. Over the next 15 years she had a composite odontoma, an impacted super-numerary tooth, two epidermal inclusion cysts, multicentric papillary—follicular adenocarcinoma of the thyroid, two tubulovillous adenomas of the duodenum in which argyrophilic cells were a prominent feature, and an adenomyoma of the gastric antrum. The presence of all of these lesions in one patient expands the spectrum of lesions seen with Gardner's syndrome and supports the concept of a generalized abnormality of growth regulation as the cause of the syndrome.

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Authors and Affiliations

  1. Division of Surgical Pathology and Cytology, Department of Pathology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Box 570, 19104, Philadelphia, Pennsylvania

    Albert A. Keshgegian M.D., Ph.D. & H. T. Enterline M.D.

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  1. Albert A. Keshgegian M.D., Ph.D.
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  2. H. T. Enterline M.D.
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Keshgegian, A.A., Enterline, H.T. Gardner's syndrome with duodenal adenomas, gastric adenomyoma and thyroid papillary—Follicular adenocarcinoma. Dis Colon Rectum 21, 255–260 (1978). https://doi.org/10.1007/BF02586699

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  • DOI: https://doi.org/10.1007/BF02586699

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