Summary
Eighty-seven colorectal carcinomas were studied histologically with special reference to grade of tumor, reactions of stromal tissue, and the morphology of regional lymph nodes. A special search was focused on the morphologic manifestations of possible host factors. The most interesting findings were: 1) nuclear grade of the tumor correlated with five-year survival; 2) the content of tumor-derived mucus was not a prognostic determinant; 3) the intensities of stromal lymphocyte and mast-cell reactions correlated with survival; 4) an active lymph-node paracortical area was almost incompatible with the appearance of nodal metastases.
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Syrjänen, K.J., Hjelt, L.H. Tumor-host relationships in colorectal carcinoma. Dis Colon Rectum 21, 29–36 (1978). https://doi.org/10.1007/BF02586543
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DOI: https://doi.org/10.1007/BF02586543