Summary
A case of villous adenoma of the colon with hyponatremia, hypovolemia, and syncope is presented. The correct diagnosis was delayed because of the prevailing idea that villous adenomas are associated with hypokalemia. The patient recovered fully after surgical removal of one of the largest villous adenomas reported in the literature. Sodium loss may be the dominant feature of this syndrome. Villous adenoma has to be included among the causes of hyponatremia.
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References
Bacon HE, Eisenberg SW: Papillary adenoma or villous tumor of the rectum and colon. Ann Surg 174: 1002, 1971
Cooling C, Marrack D: Potassium-secreting tumour of the colon. Proc R Soc Med 50: 272, 1957
DaCruz GM, Gardner JD, Peskin GW: Mechanism of diarrhea of villous adenomas. Am J Surg 115: 203, 1968
Davis JE, Seavey PW, Sessions JT Jr: Villous adenomas of the rectum and sigmoid colon with severe fluid and electrolyte depletion. Ann Surg 155: 806, 1962
Devroede GJ, Phillips SF: Conservation of sodium, chloride, and water by the human colon. Gastroenterology 56: 101, 1969
Devroede GJ, Phillips SF: Failure of the human rectum to absorb electrolytes and water. Gut 11: 438, 1970
Duthie HL, Atwell JD: The absorption of water, sodium, and potassium in the large intestine with particular reference to the effects of villous papillomas. Gut 4: 373, 1963
Gjöres JE, Örndahl B: Villous adenoma with severe fluid imbalance. Acta Chir Scand 140: 82, 1974
Hauzeur F, Arendt R: Das villöse Rektumadenom. Dtsch Z Verdau Stoffwechselkr 33: 245, 1973
Jahadi MR, Bailey W: Papillary adenomas of the colon and rectum: A twelve-year review. Dis Colon Rectum 18: 249, 1975
Mason AY: Trans-sphincteric exposure of the rectum. Ann R Coll Surg Engl 51: 320, 1972
McKittrick LS, Wheelock FC Jr: Carcinoma of the Colon. Springfield, Charles C Thomas, 1954, p 61
Quan SH, Castro EB: Papillary adenomas (villous tumors): A review of 215 cases. Dis Colon Rectum 14: 267, 1971
Roy AD, Ellis H: Potassium-secreting tumours of the large intestine. Lancet 1: 759, 1959
Schiller U, Fuchs K: Villöses Dickdermandenom mit wasser- und Electrolytverlust. Med Klin 69: 855, 1974
Shnitka TK, Friedman MH, Kidd EG, et al: Villous tumors of the rectum and colon characterized by severe fluid and electrolyte loss. Surg Gynecol Obstet 112: 609, 1961
Wrong O, Metcalfe-Gibson A: The electrolyte content of faeces. Proc R Soc Med 58: 1007, 1965
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Jeanneret-Grosjean, A.J., Thompson, W.G. Villous adenoma with hyponatremia and syncope: Report of a case. Dis Colon Rectum 21, 118–119 (1978). https://doi.org/10.1007/BF02586455
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DOI: https://doi.org/10.1007/BF02586455