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Free radical addition of thiolacetic acid to esters and amides of unsaturated acids and screening of the products for antimicrobial activity

  • Technical
  • Published:
Journal of the American Oil Chemists’ Society

Abstract

Free radical addition of thiolacetic acid to terminal and internal double bonds of mono-and diunsaturated amides, as well as to unsaturated esters, was achieved by irradiation with Cobalt-60. Screening for antimicrobial activity againstStaphylococcus aureus, Escherichia coli, Aspergillus species,Torula species, andCandida albicans indicated that terminal addition products may be more active than internal addition products.

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References

  1. Brown, R., W.E. Jones, and A.R. Pinder, J. Chem. Soc. 2123 (1951).

  2. Koenig, N.H., and D. Swern, J. Am. Chem. Soc. 79:4235 (1957).

    Article  CAS  Google Scholar 

  3. Mod, R.R., J.A. Harris, J.C. Arthur, Jr., F.C. Magne, G. Sumrell, and A.F. Novak, JAOCS 49:634 (1972).

    CAS  Google Scholar 

  4. Novak, A.F., J.M. Solar, R.R. Mod, F.C. Magne, and E.L. Skau, Ibid. 46:249 (1969).

    Article  CAS  Google Scholar 

  5. Novak, A.F., J.M. Solar, R.R. Mod, F.C. Magne, and E.L. Skau, Appl. Microbiol. 18:1050 (1969).

    CAS  Google Scholar 

  6. Mod, R.R., F.C. Magne, G. Sumrell, and A.F. Novak, JAOCS 52:455 (1975).

    CAS  Google Scholar 

  7. Magne, F.C., R.R. Mod, and E.L. Skau, Ind. Eng. Chem. 50:617 (1958).

    Article  CAS  Google Scholar 

  8. Mod, R.R., F.C. Magne, and E.L. Skau, JAOCS 41:237 (1964).

    CAS  Google Scholar 

  9. Mod, R.R., F.C. Magne, and E.L. Skau, Ibid. 42:941 (1965).

    CAS  Google Scholar 

  10. Magne, F.C., R.R. Mod, G. Sumrell, R.E. Koos, and W.E. Parker, Ibid. 52:494 (1975).

    CAS  Google Scholar 

  11. Arthur, J.C., Jr., F.A. Blouin, and R.J. Demint, “The SRRL Cobalt-60 Facility,” USDA, ARS 72-21, August 1960.

  12. Schuler, R.H., and A.O. Allen, J. Chem. Phys. 24:56 (1956).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Southern Regional Research Center, ARS, USDA, 70179, New Orleans, Louisiana

    R. R. Mod, J. A. Harris, J. C. Arthur Jr., F. C. Magne & G. Sumrell

  2. Louisiana State University, 70803, Baton Rouge, Louisiana

    A. F. Novak

Authors
  1. R. R. Mod
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  2. J. A. Harris
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  3. J. C. Arthur Jr.
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  4. F. C. Magne
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  5. G. Sumrell
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  6. A. F. Novak
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Mod, R.R., Harris, J.A., Arthur, J.C. et al. Free radical addition of thiolacetic acid to esters and amides of unsaturated acids and screening of the products for antimicrobial activity. J Am Oil Chem Soc 53, 641–643 (1976). https://doi.org/10.1007/BF02586279

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  • DOI: https://doi.org/10.1007/BF02586279

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