Summary
Plasma concentrations of insulin, growth hormone and glucagon were measured during an arginine test in obese women with normal (ON) or abnormal (OD) OGTT and in normal control subjects (N). Plasma insulin levels were higher than normal in both obese groups, while plasma growth hormone and glucagon levels were markedly reduced.
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Aguilar-Parada E., Eisentraut A. M., Unger R. H.: Pancreatic Glucagon Secretion in Normal and Diabetic Subjects — Amer. J. med. Sci.257, 415, 1969.
Andreani D., Fallucca F., Menzinger G., Gambardella S., Tamburrano S., Javicoli M.: Insulin and Glucagon in Obese Subjects — International Symposium on Insulin Synthesis and Secretion, Venezia 1973; p. 42.
Andreani D., Fallucca F., Tamburrano G., Javicoli M., Menzinger G.: Insulin, Glucagon and Growth Hormone in Primary Adult Myxoedema — Diabetologia10, 7, 1974.
Copinschi G., Wegienka L. C., Hane S., Forsham P. H.: Effect of Arginine on Serum Levels of Insulin and Growth Hormone in Obese Subjects — Metabolism16, 485, 1967.
Fajans S. S., Conn J. W.: Approach to Prediction of Diabetes Mellitus by Modification of Glucose Tolerance Test with Cortisone — Diabetes3, 296, 1954.
Grey N., Kipnis D. M.: Effect of Diet Composition on the Hyperinsulinemia of Obesity — New Engl. J. Med.285, 827, 1971.
Kalkhoff R. K., Gossain V., Matute M. L.: Plasma Glucagon in Obesity — New Engl. J. Med.289, 465, 1973.
Karam G. H., Grodsky G. M., Forsham P. H.: Excessive Insulin Response to Glucose in Obese Subjects as Measured by Immunochemical Assay — Diabetes12, 197, 1963.
Muller W. A., Faloona G. R., Unger R. H.: The Influence of the Antecedent Diet upon Glucagon and Insulin Secretion — New Engl. J. Med.285, 1450, 1971.
Perley M., Kipnis D. M.: Plasma Insulin Response to Oral and Intravenous Glucose: Studies in Normal and Diabetic Subjects — J. clin. Invest.46, 1954, 1967.
Rabinowitz D., Zierler K. L.: Forearm Metabolism in Obesity and its Response to Intrarterial Insulin: Characterization of Insulin Resistance and Evidence for Adaptive Hyperinsulinism — J. clin. Invest.41, 2173, 1962.
Tchobroutsky G., Rosselin G., Assan R., Freychet P., Dérot M.: Growth Hormone Secretion in Obese Subjects with and without Diabetes — In:Vague J. (Ed.): Physiopathology of Adipose Tissue, Excerpta Media Foundation, Amsterdam, 1969; p. 269.
Tiengo A., Assan R., Tchobroutsky G.: Metabolic and Hormonal Patterns after Three Days of Total Fasting in 27 Obese and Nonobese Subjects — In:Shafrir E. (Ed.): Impact of Insulin on Metabolic Pathways. International Symposium Commemorating the 50th Anniversary of Insulin, Jerusalem 1971; Israel J. med. Sci.8, 821, 1972.
Wise G. H., Hendler R., Felig P.: Evaluation of Alpha Cell Function by Infusion of Alanine in Normal, Diabetic and Obese Subjects — New Engl. J. Med.288, 484, 1973.
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Fallucca, F., Menzinger, G., Gambardella, S. et al. Glucagon, insulin and growth hormone response in obese women. Acta diabet. lat 12, 239–243 (1975). https://doi.org/10.1007/BF02581305
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DOI: https://doi.org/10.1007/BF02581305