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Osmotic resistance of leukocytes in patients with onset of diabetes before twenty-five years

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Summary

Osmotic resistance of leukocytes has been studied with the Storti-Pederzini method in 30 young healthy subjects and in 30 diabetics of the juvenile insulin-dependent type with variable duration of the disease and variable degrees of metabolic control. Reduced osmotic resistance, above all in the polymorphonuclear cells, has been found in diabetics. This finding did not appear to correlate with the duration of diabetes or with blood glucose level. This reduced osmotic resistance of polymorphonuclear leukocytes of diabetic patients might contribute to the deficiency in leukocyte migration and phagocytosis observed by some authors in diabetics.

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Authors and Affiliations

  1. II Divisione Di Medicina Generale, E Centro Per Gli Stati Disendocrini E Dismetabolici Dell’ospedale Civile «S. Andrea», La Spezia

    Sergio Marigo & Antonio Bersezio

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  1. Sergio Marigo
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  2. Antonio Bersezio
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Marigo, S., Bersezio, A. Osmotic resistance of leukocytes in patients with onset of diabetes before twenty-five years. Acta diabet. lat 12, 289–295 (1975). https://doi.org/10.1007/BF02581101

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