Summary
Estriol serum levels, neonatal vitality and stromal villous edema were studied in diabetic pregnancies. The average serum estriol levels in diabetic patients whose placentas had villous edema was 26.45±9.16 ng/ml. This value was significantly lower than that of the diabetic patients without villous edema (59.26±12.06 ng/ml). The average serum estriol levels in diabetic patients who gave birth to depressed newborns was 25.68±9.73 ng/ml. In diabetic women who gave birth to vigorous newborns this value was 56.57±14.10 ng/ml. The difference was statistically significant. These results and similar findings from other authors are discussed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Aladjem S.: Morphopathology of the human placental villi and the fetal outcome — J. Obstet. Gynaec. Brit. Cwlth75, 1237, 1968.
Alvarez H.: La biopsia placentaria — Arch. Ginec. Obstet.19, 3, 1961.
Alvarez H.: Placental biopsy: results, limitations and topographic differences — In:Adamsons K. (Ed.): Diagnosis and Treatment of Fetal Disorders. Springer-Verlag, Berlin-Heidelberg-New York, 1968; p. 50.
Alvarez H., Sala M. A., Benedetti W. L.: Intervillous space reduction in edematous placenta — Amer. J. Obstet. Gynec.112, 819, 1972.
Benedetti W. L., Nieto F., Sala M. A., Alvarez H.: Crecimiento ponderal fetal y placentario humano. Estimación de los 10°, 50° y 90° percentiles de las correspondientes distribuciones poblacionales — Obstet. Ginec. lat.-amer.33, 251, 1975.
Goebesman V., Katagin H., Stanczyk F., Cetrulo C. L., Freeman R. K.: Estriol assay in obstetrics — J. Steroid Biochem.6, 703, 1975.
Hull M. G. R.: The bases and application of estrogen assays on urine and blood to assess fetoplacental function in late pregnancy — J. perinat. Med.4, 137, 1976.
Jacomo H. K., Benedetti W. L., Sala M. A., Alvarez H.: Pathology of the trophoblast and fetal vessels of the placenta in maternal diabetes mellitus — Acta diabet. lat.13, 216, 1976.
Kelly V. J.: Diagnostic techniques in prepartal evaluations — Clin. Obstet. Gynec.17, 53, 1974.
Temesio P.: Manejo de la embarazada diabética — In: Diabetes y Embarazo. Ed. Panamericana, Buenos Aires, 1969; p. 114.
White P.: Pregnancy and diabetes. Medical aspects — Med. Clin. N. Amer.49, 1015, 1965.
Wilkin P., Schwers J., Cattoor J. P.: Placental pathology in relation with urinary oestriol excretion — In:Polvani F., Bompiani A. (Eds): Biological and clinical aspects of placental steroidogenesis. S. Karger, Basel, 1964; p. 107.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Giussi, G.A., Ballejo, G. & Benedetti, W.L. Estriol serum levels, neonatal vitality and stromal villous edema in diabetic pregnancies. Acta diabet. lat 16, 105–110 (1979). https://doi.org/10.1007/BF02581089
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02581089