Skip to main content
Log in

Use of an intravascular endoprosthesis (stent) to establish and maintain short-term patency of the ductus arteriosus in newborn lambs

  • Laboratory Investigation
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

The feasibility of stenting the ductus arteriosus with a balloon-expandable vascular endoprosthesis was tested in 8 newborn lambs. Tantalum wire and stainless steel mesh coronary stents were implanted antegrade or retrograde by percutaneous transfemoral catheterization. One lamb died during the procedure from perforation of the aorta. In 7 lambs, the ductus arteriosus was crossed using endhole catheters and wires, and stents mounted on angioplasty catheters were expanded in the ductus arterisus. Six lambs had successful implantation and had maintained a sizeable patent ductus arteriosus at 2 h. We conclude that the feasibility of percutaneous stenting of the newborn ductus was demonstrated. By providing patency of the ductus arteriosus, stents may offer nonsurgical alternatives for palliation of cyanotic congenital heart disease and hypoplastic left heart syndrome

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Schatz RA (1989) A view of vascular stents (editorial). Circulation 79:445–457

    PubMed  CAS  Google Scholar 

  2. Schatz RA, Palmaz JC, Tio FO, Garcia F, Garcia O, Reuter SR (1987) Balloon-expandable intracoronary stents in the adult dog. Circulation 76:450–457

    PubMed  CAS  Google Scholar 

  3. Sigwart U, Puel J, Mirkovitch V, Joffre F, Kappenberger L (1987) Intravascular stents to prevent occlusion and restenosis after transluminal angioplasty. N Engl J Med 316:701–706

    Article  PubMed  CAS  Google Scholar 

  4. Levine MJ, Leonard BM, Burke JA, Nash ID, Safian RD, Diver DJ, Baim DS (1990) Clinical and angiographic results of balloon-expandable intracoronary stents in right coronary artery stenoses. J Am Coll Cardiol 16:332–339

    Article  PubMed  CAS  Google Scholar 

  5. Palmaz JC, Sibbitt RR, Reuter SR, Tio FO, Rice WJ (1985) Expandable intraluminal graft: A preliminary study. Radiology 156:73–77

    PubMed  CAS  Google Scholar 

  6. Palmaz JC, Garcia OJ, Schatz RA, Rees CR, Roerren T, Richter GM, Noeldge G, Gardiner GA, Becker GJ, Walker C, Stagg J., Katzen BT, Dake MD, Paolini, RM, McLean GK, Lammer J, Schwarten DE, Tio FO, Root HD, Rogers W (1990) Placement of balloon-expandable intraluminal stents in iliac arteries: First 171 procedures. Radiology 174:969–975

    PubMed  CAS  Google Scholar 

  7. Mullins CE, O'Laughlin MP, Vick GW, Mayer DC, Myers TJ, Kearney DL, Schatz RA, Palmaz JC (1988) Implantation of balloon-expandable intravascular grafts by catheterization in pulmonary arteries and systemic veins. Circulation 77:188–199

    PubMed  CAS  Google Scholar 

  8. Ellis SG, Savage M, Baim D, Hirshfeld J, Cleman M, Teirstein P, Toppol EJ (1990) Intracoronary stenting to prevent restenosis: Preliminary results of a multicenter study using the Palmaz-Schatz stent suggest benefit in selected high risk patients. JACC 15:118A

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

The opinions expressed are those of the authors and are not to be construed as official or as reflecting the views of the Army or the Department of Defense.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Moore, J.W., Kirby, W.C., Lovett, E.J. et al. Use of an intravascular endoprosthesis (stent) to establish and maintain short-term patency of the ductus arteriosus in newborn lambs. Cardiovasc Intervent Radiol 14, 299–301 (1991). https://doi.org/10.1007/BF02578454

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02578454

Key words

Navigation