Abstract
The initial site of occlusion of the intrahepatic microvasculature in rats following hepatic artery embolization was studied by scanning electron microscopy of microvasculature casts. The rats were divided into four groups: embolization with gelatin powder (n=3), polyvinyl alcohol (n=3, 125–150 μm), gelatin sponge (n=3, 212–250 μm), and ionized oil. Not only the hepatic arteires but also vessels in the peribiliary plexus were occluded. However, the size of the hepatic arteries and vessels of the peribiliary plexus occluded correlated with the size of the embolic material, except in the case of the gelatin powder which occluded vessels smaller than the particle size.
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Chuang VP, Wallace S (1981) Hepatic artery embolization in the treatment of hepatic neoplasms. Radiology 140:51–58
Clouse ME, Lee RGL, Duszlak EJ, Lokich JJ, Trey C, Alday MR, Yoburn DC, Diamond J, Crosson AW, Costello P (1983) Peripheral hepatic artery embolization for primary and secondary hepatic neoplasms. Radiology 147:407–411
Yamada R, Sato M, Kawabata M, Nakatsuka H, Nakamura K, Takashima S (1983) Hepatic artery embolization in 120 patients with unresectable hepatoma. Radiology 148:397–401
Cho KJ, Lunderquist A (1983) Experimental hepatic artery embolization with Gelfoam powder. Microfil perfusion study of the rabbit liver. Invest Radiol 18:189–193
Stridbeck H, Lorelius LE, Pirtle TE (1984) Development of collateral circulation following distal embolization of hepatic artery in pigs. Cardiovasc Intervent Radiol 7:240–244
Cho KJ, Fanders B, Smid A, McLaughlin P (1989) Experimental hepatic artery embolization with a collagen embolic agent in rabbits. A microcirculatory study. Invest Radiol 24:371–374
Kan X, Ivancev K, Hägerstrand I, Chuang VP, Lunderquist A (1989) In vivo microscopy of the liver after injection of Lipiodol into the hepatic artery and portal vein in the rat. Acta Radiologica 30:419–425
Ohtani O, Murakami T (1978) Peribiliary portal system in the rat liver as studied by the injection replica scanning electron microscope method. Scanning Electron Microsc 11:241–244
Nopanitaya W, Grisham JW, Aghajanian JG, Carson JL (1978) Intrahepatic microcirculation: SEM study of the terminal distribution of the hepatic artery. Scanning Electron Microsc 11:837–840
Yamamoto K, Sherman I, Phillips MJ, Fisher MM (1985) Three-dimensional observations of the hepatic arterial terminations in rat, hamster and human liver by scanning electron microscopy of microvascular casts. Hepatology 5:452–456
Makuuchi M, Sukigara M, Mori T, Kobayashi J, Yamazaki S, Hasegawa H, Moriyama N, Takayasu K, Hirohashi S (1985) Bile duct necrosis: complication of transcatheter hepatic arterial embolization. Radiology 156:331–334.
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Demachi, H., Matsui, O. & Takashima, T. Scanning electron microscopy of intrahepatic microvasculature casts following experimental hepatic artery embolization. Cardiovasc Intervent Radiol 14, 158–162 (1991). https://doi.org/10.1007/BF02577719
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DOI: https://doi.org/10.1007/BF02577719