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Deep vein thrombosis and pulmonary embolism: Clinical presentation and pathophysiologic consequences

  • I. Diagnosis and Treatment of Deep Venous Disease and Pulmonary Embolism
  • Published:
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Abstract

Deep vein thrombosis (DVT) and pulmonary embolism (PE) are both characterized by unreliable clinical diagnosis and significant long-term sequelae. In patients with DVT, popliteal valvular insufficiency is associated with increased risk for postphlebitic syndrome. Current data show thrombolytic therapy to be more effective than anticoagulation for DVT, accomplishing significant or complete clearing of the deep venous system in nearly half of all patients treated. Results of investigation show lytic therapy to also be more, effective than heaparin in treatment of PE, both in terms of acute resolution and long-term function.

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Authors and Affiliations

  1. Section of Vascular Surgery, Temple University Hospital, 3401 North Broad Street, 19140, Philadelphia, PA, USA

    Anthony J. Comerota M.D., F.A.C.S.

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  1. Anthony J. Comerota M.D., F.A.C.S.
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Comerota, A.J. Deep vein thrombosis and pulmonary embolism: Clinical presentation and pathophysiologic consequences. Cardiovasc Intervent Radiol 11 (Suppl 1), S9–S14 (1988). https://doi.org/10.1007/BF02577090

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  • DOI: https://doi.org/10.1007/BF02577090

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