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Molecular co-crystals of carboxylic acids, part 29. The effect of competitive interactions on adduct formation involving 2-aminopyrimidine: the crystal structure of the 1∶1 adduct of 2-aminopyrimidine with indole-2-carboxylic acid

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Abstract

The crystal structure of the 1∶1 adduct of 2-aminopyrimidine with indole-2-carboxylic acid has been determined by single crystal X-ray diffraction, revealing a novel interactive mode. The utility of 2-aminopyrimidine in formation of stable hydrogen-bonded networks with carboxylic acids is discussed and the modes of interaction are reviewed.

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References

  1. [Cu2(RCO2)2(2-AP)]n a)R=CH3: Smith, G.; Kennard, C.H.L.; Byriel, K.A.Polyhedron 1991,10, 873. (b)R=o-Cl·C6H4·OCH2: Smith, G.; O'Reilly, E.J.; Kennard, C.H.L.; White, A.J. Chem. Soc. Dalton Trans. 1985,243. (c) R=o-CH3CO·C6H4·OCH2: Smith, G.; O'Reilly, E.J.; Carrell, H.L.; Carrell, C.J.; Kennard, C.H.L.Polyhedron 1996,15, 1995.

    Article  CAS  Google Scholar 

  2. Etter, M.C.J. Phys. Chem. 1991,95, 4601.

    Article  CAS  Google Scholar 

  3. Etter, M.C.; Adsmond, D.J. Chem. Soc., Chem. Commun. 1990, 589.

  4. Adsmond, D.A. Thesis, University of Minnesota, 1991.

  5. Berstein, J.; Etter, M.C.; Leiserowitz L. InStructure Correlation; Bürgi, H.-B.; Dunitz, J.D., Eds.; VCH: Weinheim, 1994; Vol. 2, pp 490–507.

    Google Scholar 

  6. Lynch, D.E.; Smith, G.; Freney, D.; Byriel, K.A.; Kennard, C.H.L.Aust. J. Chem. 1994,47, 1097.

    Article  CAS  Google Scholar 

  7. Smith, G.; Gentner, J.M.; Lynch, D.E.; Byriel, K.A.; Kennard, C.H.L.Aust. J. Chem. 1995,48, 1151.

    Article  CAS  Google Scholar 

  8. Byriel, K.A.; Kennard, C.H.L.; Lynch, D.E.; Smith, G.; Thompson, J.G.Aust. J. Chem. 1992,45, 969.

    Article  CAS  Google Scholar 

  9. Shimoni, L.; Glusker, J.P.; Bock, C.W.J. Phys. Chem. 1996,100, 2957.

    Article  CAS  Google Scholar 

  10. Sheldrick, G.M.SHELXS-86, Structure Solution Package; University of Göttingen: Federal Republic of Germany, 1986.

    Google Scholar 

  11. Sheldrick, G.M.SHELXL-93, Program for Crystal Structure Determination; University of Göttingen: Federal Republic of Germany, 1993.

    Google Scholar 

  12. Gellbert, R.W.; Hsu, I.-N.Acta Crystallogr. 1981,A37, C93.

    Article  Google Scholar 

  13. Kim, H.S.; Jeffrey, G.A.Acta Crystallogr. 1971,B27, 1123.

    Article  CAS  Google Scholar 

  14. Tamura, C.; Yoshikawa, M.; Sato, S.; Hata, T.Chem. Lett. 1973, 1221.

  15. Kartha, G.; Varughese, K.I.Acta Crystallogr. 1978,A34, S90.

    Google Scholar 

  16. Shimizu, N.; Nishigaki, S.; Nakai, Y.; Osaki, K.Acta Crystallogr. 1983,C39, 891.

    Google Scholar 

  17. Bryant, P.K.; Colby, J.; Jenks, R.G.; Lowe, P.R.; Schwalbe, C.H.Acta Crystallogr. 1984,A40, C79.

    Google Scholar 

  18. Patel, U.; Haridas, M.; Singh, T.P.Acta Crystallogr. 1988,C44, 1264.

    Google Scholar 

  19. Tamara, C.; Sato, S.; Hata, T.Bull. Chem. Soc. Jpn. 1973,46, 2388.

    Article  Google Scholar 

  20. Unpublished results.

  21. Lynch, D.E.; Smith, G.; Byriel, K.A.; Kennard, C.H.L.Z Kristallogr. 1992,200, 73.

    Article  CAS  Google Scholar 

  22. Lynch, D.E.; Smith G.; Byriel, K.A.; Kennard, C.H.L.Acta Crystallogr. 1992,C48, 1265.

    Google Scholar 

  23. Desiraju, G.R.J. Chem. Soc. Chem. Commun. 1991, 427.

  24. Neidle, S.Cancer Top. 1994,9(10), 14.

    Google Scholar 

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Authors and Affiliations

  1. School of Natural and Environmental Sciences, Coventry University, Priory Street, CV1 5FB, Coventry, UK

    Daniel E. Lynch & Tariq Latif

  2. School of Physical Sciences, Queensland University of Technology, P.O. Box 2434, Q4001, Brisbane, Australia

    Graham Smith

  3. Department of Chemistry, The University of Queensland, Q4072, Brisbane, Australia

    Karl A. Byriel & Colin H. L. Kennard

Authors
  1. Daniel E. Lynch
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  2. Tariq Latif
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  3. Graham Smith
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  4. Karl A. Byriel
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  5. Colin H. L. Kennard
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Additional information

Part 28.,Aust. J. Chem., 1997, (submitted).

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Lynch, D.E., Latif, T., Smith, G. et al. Molecular co-crystals of carboxylic acids, part 29. The effect of competitive interactions on adduct formation involving 2-aminopyrimidine: the crystal structure of the 1∶1 adduct of 2-aminopyrimidine with indole-2-carboxylic acid. J Chem Crystallogr 27, 567–575 (1997). https://doi.org/10.1007/BF02576455

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  • DOI: https://doi.org/10.1007/BF02576455

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