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Preoperative chemoradiation for rectal cancer: A different perspective

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References

  1. Weber TK. Preoperative chemoradiation for rectal cancer: “Apples & Pears, Tables and Chairs....Ann Surg Oncol 2002; 9:532–4.

    Article  PubMed  Google Scholar 

  2. Bozzetti F, Andreola S, Baratti D, et al. Preoperative chemoradiation in patients with resectable rectal cancer: results on tumor response.Ann Surg Oncol 2002;9:444–9.

    Article  PubMed  Google Scholar 

  3. Camma C, Giunta M, Fiorica F, Craxi A, Cottone M. Preoperative radiotherapy for resectable rectal cancer: a meta-analysis.JAMA 2000;284:1008–15.

    Article  PubMed  CAS  Google Scholar 

  4. McCulloch P, Taylor I, Sasako M, Lovett B, Griffin D. Randomised trials in surgery: problems and possible solutions.BMJ 2002; 324:1448–51.

    Article  PubMed  Google Scholar 

  5. Rouanet P, Saint-Aubert B, Lemanski C, et al. Restorative and nonrestorative surgery for low rectal cancer after high-dose radiation long-term oncologic and functional results.Dis Colon Rectum 2002;45:305–13.

    Article  PubMed  Google Scholar 

  6. Nakagawa WT, Rossi BM, de O Ferreira F, et al. Chemoradiation instead of surgery to treat mid and low rectal tumors: is it safe?Ann Surg Oncol 2002;9:568–73.

    Article  PubMed  Google Scholar 

  7. Rich TA, Skibber JM, Ajani JA, et al. Preoperative infusional chemotheradiation therapy for stage T3 rectal cancer.Int J Radiat Oncol Biol Phys 1995;32:1025–9.

    Article  PubMed  CAS  Google Scholar 

  8. Minsky BD, Cohen AM, Enker WE, et al. Preoperative 5-FU, low-dose leucovorin, and radiation therapy for locally advanced and unresectable rectal cancer.Int J Radiat Oncol Biol Phys 1997;37:289–95.

    Article  PubMed  CAS  Google Scholar 

  9. Bozzetti F, Baratti D, Andreola S, et al. Preoperative radiation therapy for T2–T3 cancers of the middle-low rectum.Cancer 1999;86:398–404.

    Article  PubMed  CAS  Google Scholar 

  10. Theodoropoulos G, Wise WE, Padmanabhan A, et al. T-level downstaging and complete pathologic response after preoperative chemoradiation for advanced rectal cancer results in decreased recurrence and improved disease-free survival.Dis Colon Rectum 2002;45:895–903.

    Article  PubMed  Google Scholar 

  11. Bosset JF, Magnin V, Maingon P, et al. Preoperative radio-chemotherapy in rectal cancer: long-term results of a phase II trial.Int J Radiat Oncol Biol Phys 2000;46:323–7.

    Article  PubMed  CAS  Google Scholar 

  12. Kaminsky-Forrett MC, Conroy T, Luporsi E, et al. Prognostic implications following preoperative radiation for operable T3–T4 rectal cancer.Int J Radiat Oncol Biol Phys 1998;42:935–41.

    Article  PubMed  CAS  Google Scholar 

  13. Ruo L, Tickoo S, Klimstra TS, et al. Long-term prognostic significance of extent of rectal cancer and response to pre-operative radiation and chemotherapy.Ann Surg Oncol 2002;236:75–81.

    Google Scholar 

  14. Marks G, Mohiuddin MM, Masoni L, Pecchioli L. High-dose preoperative radiation and full-thickness local excision. A new option for patients with select cancer of the rectum.Dis Colon Rectum 1990;33:735–9.

    Article  PubMed  CAS  Google Scholar 

  15. Wagman R, Minsky BD, Cohen AM, Guillen JG, Paty PP. Sphincter preservation in rectal cancer with preoperative radiation therapy and coloanal anastomosis: long term follow up.Int J Radiat Oncol Biol Phys 1998;42:51–7.

    Article  PubMed  CAS  Google Scholar 

  16. Hyams DM, Mamounas EP, Petrelli N, et al. A clinical trial to evaluation the worth of preoperative multimodality therapy in patients with operable cancer of the rectum: a progress report of National Surgical Breast and Bowel Project Protocol R-03.Dis Colon Rectum 1997;40:131–9.

    Article  PubMed  CAS  Google Scholar 

  17. Janjan NA, Crane CN, Feig BW, et al. Prospective trial of preoperative concomitant boost radiotherapy with continuous infusion of 5-fluorouracil for locally advance rectal cancer.Int J Radiat Oncol Biol Phys 2000;47:713–8.

    Article  PubMed  CAS  Google Scholar 

  18. Kim CJ, Yeatman TJ, Coppola D, et al. Local excision of T2 and T3 rectal cancer after down staging chemoradiation.Ann Surg 2001;234:352–8.

    Article  PubMed  CAS  Google Scholar 

  19. Mandard AM, Dalibard F, Mandard JC, et al. Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations.Cancer 1994;73:2680–6.

    Article  PubMed  CAS  Google Scholar 

  20. Bozzetti F, Mariani L, Miceli R, et al. Cancer of the low and middle rectum: local and distant recurrences, and survival in 350 radically resected patients.J Surg Oncol 1996;62:207–13.

    Article  PubMed  CAS  Google Scholar 

  21. Halpern SD, Karlwish JH, Berlin JA. The continuing unethical conduct of underpowered clinical trials.JAMA 2002;288:358–62.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Instituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy

    Federico Bozzetti MD

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  1. Federico Bozzetti MD
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Bozzetti, F. Preoperative chemoradiation for rectal cancer: A different perspective. Annals of Surgical Oncology 9, 1033–1034 (2002). https://doi.org/10.1007/BF02574524

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