Summary
The fatty acid composition of total lipid and phospholipid contents was determined in the amniotic fluid of normal and diabetic pregnant patients. Disturbance of lipid metabolism which is not related to the severity of diabetes, causes difficulties in the determination of L/S ratio. The palmitic acid content of total lipid and lecithin is increased in diabetic pregnancy. The lecithin synthesis is significantly decreased as result of a transitory or prolonged acidosis.
Zusammenfassung
Im Fruchtwasser der zuckerkranken Schwangeren wurden neben der Gesamtlipoid- und Phospholipid-Konzentration die Zusammensetzung der Fettsäure der Amnionflüssigkeit, die Menge der gebundenen Palmitinsäure bestimmt und mit den der gesunden Schwangeren verglichen. Die Fettstoffwechselstörung läuft nicht parallel mit der Schwere der Zuckerkrankheit, und die oberflächenaktive Lipidbestimmung ist erschwert.
In dem Fruchtwasser der Diabetiker ist die Menge der zur Gesamtlipoidenund zur Lecithin-gebundenen Palmitinsäure erhöht. Die Lecithin-Produktion bei transitorischen oder ständigen Acidosen vermindert sich bedeutend.
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Szalay, J., Lukacs, E. Palmitic acid concentration of amniotic fluid in diabetic pregnancy. Arch. Gynak. 222, 279–283 (1977). https://doi.org/10.1007/BF02570654
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DOI: https://doi.org/10.1007/BF02570654