Skip to main content
Log in

Juvenile rheumatoid arthritis and renal amyloidosis

Case report

  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

Clinical renal abnormalities, including haematuria, proteinuria, abnormal urinary sediment, decreased renal functions and hypertension are relatively common in children with juvenile rheumatoid arthritis (JRA). These findings may be due to renal amyloidosis or administration of drugs that are potentially nephrotoxic.

The case of an 11 years old boy diagnosed as JRA at 4.5 months of age and treated with steroids for 10 years is presented. In his history he had hypertension for 5 years and cataract for one year. Renal biopsy was done to evaluate the aetiology for proteinuria, which was overlooked before his admission to our Department. Secondary renal amyloidosis due to JRA was found at biopsy.

The importance of investigation for amyloidosis during the long-term follow-up of JRA is reemphasized.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. David, J., Wood, P.: Reactive amyloidosis.Arch. Dis. Child., 67, 258 (1992).

    Article  PubMed  CAS  Google Scholar 

  2. Stoeber, E.: Progression in juvenile chronic arthritis.Eur. J. Pediatr., 135, 225 (1981).

    Article  PubMed  CAS  Google Scholar 

  3. Beşbaş, N., Saatci, Ü., Bakkaloĝlu, A., Özen, S.: Amyloidosis of juvenile chronic arthritis in Turkish children.Scand. J. Rheumatol., 21, 257 (1992).

    PubMed  Google Scholar 

  4. Özdoğan, H., Kasapcopur, O., Dede, H., Arisoy, N., Beceren, T., Yurdakul, S., Yazici, H.: Juvenile chronic arthritis in a Turkish population.Clin. Exp. Rheumatol., 9, 431 (1991).

    PubMed  Google Scholar 

  5. Göçen, K. Ş., Tinaztepe, K., Tinaztepe B.: Renal amyloidosis in childhood: Clinicopathological study of 174 cases (in Turkish).Çocuk Sağliği ve Hastaliklari dergisi, 34, 75 (1991).

    Google Scholar 

  6. Werdling, D., Humbert, P. G., Billerey, C., Fest, T., Duberd, J. L.: Adult onset Still's disease and related renal amyloidosis.Ann. Rheum. Dis., 50, 257 (1991).

    Google Scholar 

  7. Çamsari, T., Erol, S. K., Akbaylar, H., Kovanlikaya, I., Kazanci, L., Ulusan, Z.: Reactive amyloidosis in juvenile rheumatoid arthritis (in Turkish).Dokuz Eylül Üniversitesi Tip Fakültesi Dergisi, 3, 176 (1988).

    Google Scholar 

  8. Mauny, C. P. I., Teppo, A. M., Wafin, F., Wegelius, O., Friman, C., Koskemies, S.: Class specific rheumatoid factors, DR antigen and amyloidosis in rheumatoid arthritis.Ann. Rheum. Dis. 47, 546 (1988).

    Article  Google Scholar 

  9. Deschenes, G., Prieur, A. M., Hayem, F., Broyer, M., Gubler, M. C.: Renal amyloidosis in juvenile chronic arthritis evaluation after chlorambucil treatment.Pediatr. Nephrol., 4, 463 (1990).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kavukçu, S., Türkmen, M., Saatçi, O. et al. Juvenile rheumatoid arthritis and renal amyloidosis. International Urology and Nephrology 27, 251–256 (1995). https://doi.org/10.1007/BF02564758

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02564758

Keywords

Navigation