Skip to main content
SpringerLink
Log in

Emergency treatment of renal colic with intravenous Ketoprofen

  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

The non-steroidal anti-inflammatory drug (NSAID) Ketoprofen (Profenid) is used as intravenous monotherapy incorporated in 0.9% normal saline solution (100 mg Ketoprofen ampoule +200 ml normal saline) in the treatment of renal colic.

We present our experience in 65 patients complaining of clinically diagnosed renal colic who were treated by intravenous saline-Ketoprofen. Prospective investigations revaled urinary calculi in 51 patients, oxaluria (crystalluria) in 5, acute colitis in 2, severe myositis in 2, negative investigations in 3 and radiculitis in 2 patients.

Positive response was observed in 93.8% of patients as far as pain relief is concerned. Pain relief started within 5–7 minutes after beginning the infusion. Duration of analgesic effect ranged between 4 and 12 hours. Repeating the injection was done for maintenance of analgesia.

Side effects included drowsiness in 2 patients, palpitation in 1 patient, epigastric pain in 1, muscular cramp in 1 patient.

Ketoprofen, an antiprostaglandin, is a powerful anti-inflammatory and potent analgesic. Intravenous saline-Ketoprofen is a good emergency treatment for acute episodes of renal colic.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Allen, J. T., Vaughan, D. E., Gillenwater, J. Y.: The effect of indomethacin on renal blood flow and ureteral pressure in unilateral ureteral obstruction in awake dogs.Invest. Urol., 15, 324 (1978).

    PubMed  CAS  Google Scholar 

  2. Buck, A. C., Lote, C. J., Sampson, W. F.: The influence of renal prostaglandins on urinary calcium excretion in idiopathic urolithiasis.J. Urol., 129, 421 (1983).

    PubMed  CAS  Google Scholar 

  3. Dretler, S. P., Keating, M. A., Riley, J.: Algorithm for management of ureteral calculi.J. Urol., 136, 1190 (1986).

    PubMed  CAS  Google Scholar 

  4. Morrisson, A. R.: Prostaglandins and the kidney.Am. J. Med., 69, 171 (1980).

    Article  Google Scholar 

  5. Philippe Khoury: Profenid injection. Rhone—Poulenc Rorer Doma, Vol. 1, No. 5, 1992.

Download references

Author information

Authors and Affiliations

  1. Departments of Urology and Nephrology, Ain Shams University, Cairo, Egypt

    M. A. El-Baz & M. El-Tayeb Nasser

Authors
  1. M. A. El-Baz
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. El-Tayeb Nasser
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

El-Baz, M.A., Nasser, M.ET. Emergency treatment of renal colic with intravenous Ketoprofen. International Urology and Nephrology 27, 245–249 (1995). https://doi.org/10.1007/BF02564757

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02564757

Keywords

Search

Navigation