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Fungal resistance

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Summary

Fungal resistance is caused by an acquisition of intrinsically resistant species, by selection of resistant strains from a population or by mutation of an initially susceptible strain. According to different classes of antimycotics there are different resistance mechanisms: differences in the uptake mechanisms, drug target alterations, mostly the ergosterolbiosynthesis pathway, and the efflux or pumping mechanisms to the outside.

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Authors and Affiliations

  1. Universitäts-Klinik für Innere Medizin A, Loefflerstr 23 a, D-17489, Greifswald, Germany

    H. Bernhardt,  K. Zimmermann &  M. Knoke

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  1. H. Bernhardt
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  2. K. Zimmermann
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  3. M. Knoke
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Bernhardt, H., Zimmermann, K. & Knoke, M. Fungal resistance. Infection 27 (Suppl 2), S52–S54 (1999). https://doi.org/10.1007/BF02561673

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