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Compartment modeling from tracer experiments

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Abstract

Anelementary system is defined as two compartments, one the immediate and unique precursor of the other. By synthesizing a number of elementary systems, we can obtain a system with any givenweight, transfer time anddispersion. A criterion is presented to choose the best model of a given system, i.e. a system with the same above parameters and composed of a minimum number of elementary systems.

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Literature

  • Rescigno, A. 1960. “Synthesis of a Multicompartmented Biological Model”.Biochim. Biophys. Acta,37, 463–468.

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  • Rescigno, A. 1973. “On Transfer Times in Tracer Experiments”.J. Theoret. Biol. (in press).

  • Rescigno, A. and L. D. Michels. 1973. “On Dispersion in Tracer Experiments”.Ibid. (submitted).

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Authors and Affiliations

  1. Department of Physiology, University of Minnesota, Minneapolis, Minnesota

    Aldo Rescigno & Lester Michels

Authors
  1. Aldo Rescigno
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  2. Lester Michels
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Additional information

Supported in part by NIH grant NO. GM-572.

Supported by PHS Training grant No. 2T01 HE05138-17 from the National Heart Institute.

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Rescigno, A., Michels, L. Compartment modeling from tracer experiments. Bltn Mathcal Biology 35, 245–257 (1973). https://doi.org/10.1007/BF02558810

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  • DOI: https://doi.org/10.1007/BF02558810

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