Skip to main content

Advertisement

Log in

Effect of total colectomy and mucosal proctectomy on intestinal absorptive capacity in dogs

  • Published:
Diseases of the Colon & Rectum

Abstract

Changes in intestinal absorptive capacity for water and electrolytes were investigated in dogs after total colectomy and mucosal proctectomy reconstructed with interposing jejunum into the anorectal area. Rate of abosorption of water and sodium from the ileum increased significantly at 29 weeks postoperatively. The absorption of water, sodium, and chloride in the jejunum was significantly higher than in the neorectum. The net secretion rate of potassium increased significantly in the ileum and neorectum. The authors suggest that intestinal adaptation achieved after proctocolectomy is enhanced in the jejunum and ileum rather than in the neorectum.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Taylor BM, Cranley B, Kelly KA, Phillips SF, Beart RW Jr, Dozois RR. A clinico-physiological comparison of ileal pouch-anal and straight ileoanal anastomoses. Ann Surg 1983;198:462–8.

    Article  PubMed  CAS  Google Scholar 

  2. Pemberton JH, Heppell J, Beart RW Jr, Dozois RR, Telander RL. Endorectal ileoanal anastomosis. Surg Gynecol Obstet 1982;155:417–24.

    PubMed  CAS  Google Scholar 

  3. Kojima Y, Sanada Y, Fonkalsrud EW. Comparison of endorectal ileal pullthrough following colectomy with and without ileal reservoir. J Pediatr Surg 1982;17:653–9.

    Article  PubMed  CAS  Google Scholar 

  4. Schraut WH, Rosemurgy AS, Wang CH, Block GE. Determinants of optimal resuls after ileoanal anastomosis: anal proximity and motility patterns of the ileal reservoir. World J Surg 1983;7:400–8.

    Article  PubMed  CAS  Google Scholar 

  5. Nicholls RJ, Belliveau P, Neill M, Wilks M, Tabaqchali S. Restorative proctocolectomy with ileal reservoir: a pathophysiological assessment. Gut 1981;22:462–8.

    PubMed  CAS  Google Scholar 

  6. Malawer SJ, Powell DW. An improved turbidimetric analysis of polyethylene glycol utilizing an emulsifier. Gastroenterology 1967;53:250–6.

    CAS  Google Scholar 

  7. Powell DW, Malawer SJ. Relationship between water and solute transport from isosmotic solutions by rat intestine in vivo. Am J Physiol 1968;215:49–55.

    PubMed  CAS  Google Scholar 

  8. Wright HK, Cleveland JC, Tilson MD, Herskovic T. Morphology and absorptive capacity of the ileum after ileostomy in man. Am J Surg 1969;117:242–5.

    Article  PubMed  CAS  Google Scholar 

  9. Turnberg LA. Potassium transport in the human small bowel. Gut 1971;12:811–8.

    PubMed  CAS  Google Scholar 

  10. Hawker PC, Morris AI, McKay J, Turnberg LA. Study of ion transport across biopsies of ileostomyin vitro: search for evidence of intestinal “adaptation’ after colectomy. Gut 1980;21: 146–50.

    PubMed  CAS  Google Scholar 

  11. Gadacz TR, Kelly KA, Phillips SF. The continent ileal pouch: absorptive and motor features. Gastroenterology 1977;72:1287–91.

    PubMed  CAS  Google Scholar 

  12. Prado p. de Moraes-Filho J, Salas-Coll C, Blendis L, Edmonds CJ. Electrical potential difference and absorption of water, sodium, and potassium by the terminal ileum of ileostomy patients. Gut 1974;15:977–81.

    Google Scholar 

  13. Wright HK, Poskitt T, Cleveland JC, Herskovic T. The effect of total colectomy on morphology and absorptive capacity of ileum in the rat. J Surg Res 1969;9:301–4.

    Article  PubMed  CAS  Google Scholar 

  14. LeVeen HH, Lyons A, Becker E. Physiologic adaptation to ileostomy. Am J Surg 1962;103:35–41.

    Article  PubMed  CAS  Google Scholar 

  15. Devroede GJ, Phillips SF, Code CF, Lind JF. Regional differences in rates of insorption of sodium and water from the human large intestine. Can J Physiol Pharmacol 1970;49:1023–9.

    Google Scholar 

  16. Hill MJ, Drasar BS. Degradation of bile salts by human intestinal bacteria. Gut 1968;9:22–7.

    PubMed  CAS  Google Scholar 

  17. Pedersen BH, Simonsen L, Hansen LK, et al. Bile acid malabsorption in patients with an ileum reservoir with a long efferent leg to an anal anastomosis. Scand J Gastroenterol 1985;20:995–1000.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

About this article

Cite this article

Mibu, R., Itoh, H. & Nakayama, F. Effect of total colectomy and mucosal proctectomy on intestinal absorptive capacity in dogs. Dis Colon Rectum 30, 47–51 (1987). https://doi.org/10.1007/BF02556924

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02556924

Key words

Navigation