Summary
Serum calcium, ionized calcium, and phosphorus have been obtained at hourly intervals in nine healthy postmenopausal women. The hourly means of ionized calcium and phosphorus demonstrate significant diurnal variation with a similar apogee, nadir, and periodicity (24 hours). These results are distinct from the diurnal variation of ionized calcium and phosphorus previously reported for young men and provide more evidence of an altered mineral hemostasis in postmenopausal women.
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Markowitz M, Rotkin L, Rosen JF (1981) Circadian rhythm of blood minerals in humans. Science 213:672–674
Jubiz W, Canterbury JM, Reiss E, Tyler FH (1972) Circadian rhythm in serum parathyroid hormone concentration in human subjects: correlation with serum calcium, phosphate, albumin, and growth hormone levels. J Clin Invest 51:2040
Arnaud CD, Tsao HS, Littledike T (1971) Radioimmunoassay of human parathyroid hormone in serum. J Clin Invest 50:21
Riggs BL, Walner HW, Seeman E, et al. (1983) Changes in bone mineral density of the proximal femur and spine with aging. J Clin Invest 70:716–723
Avioli LV Osteoporosis: pathogenesis and therapy. In: Avioli LV, Krane SM (eds) Metabolic bone disease Vol. 1 pp 307–385
Perry HM III, Fallon MD, Bergfeld M, Teitelbaum SL, Avioli LV (1982) Osteoporosis in young men: a syndrome of hypercalciuria and accelerated bone turnover. Arch Int Med 142:1295–1298
Heaney RP (1965) A unified concept of osteoporosis. Am J Med 39:877–880
Jasani C, Nordin BEC, Smith DA, Swanson I (1965) Spinal osteoporosis and the menopause. Proc R Soc Mid 58:441–444
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Perry, H.M., Province, M.A., Droke, D.M. et al. Diurnal variation of serum calcium and phosphorus in postmenopausal women. Calcif Tissue Int 38, 115–118 (1986). https://doi.org/10.1007/BF02556839
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DOI: https://doi.org/10.1007/BF02556839