Abstract
A 40-year-old black male had unresectable giant condylomata acuminata of the anorectum with invasive, squamous-cell carcinoma. He was treated with intravenous 5-fluorouracil and mitomycin-C and with extended field radiation to the primary lesion. An abdominoperineal resection was performed, and the surgical specimen contained no residual cancer. Three years after diagnosis, the patient has no recurrent cancer. This case illustrates that otherwise unresectable giant condylomata acuminata with invasive carcinoma may be rendered operable with chemotherapy and radiation.
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This work was supported by NIH Grant 1T32 AM07488. Dr. Butler is a recipient of the Frommeyer Fellowship award.
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Butler, T.W., Gefter, J., Kleto, D. et al. Squamous-cell carcinoma of the anus in condyloma acuminatum. Dis Colon Rectum 30, 293–295 (1987). https://doi.org/10.1007/BF02556178
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DOI: https://doi.org/10.1007/BF02556178