Skip to main content
Log in

Symptomatic recurrences of carcinoma of the rectum and sigmoid

The influence of radiotherapy on the quality of life

  • Published:
Diseases of the Colon & Rectum

Abstract

One hundred forty-three patients irradiated for locoregional recurrences after curative surgery for cancer of the rectum and sigmoid were studied retrospectively. An analysis was made of the symptomatic response and survival in the total series and in three subgroups treated with different dose levels (40 Gy or lower, between 40 and 50 Gy, 50 Gy or higher). The symptom-free period was calculated as percent of the overall survival. Symptomatic control was obtained in 80.4 percent of the cases, and the crude patient survival rate was 17.5 percent at two years. No significant difference was found in the three subgroups treated with different dose levels. The cumulative time/patient asymptomatic periods in the total series and in the three subgroups were 31.5, 30.2, 31.8, and 31.9 percent respectively, of the survival period.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Whiteley HW Jr, Stearns MW Jr, Leaming RH, Deddish MR. Radiation therapy in the palliative management of patients with recurrent cancer of the rectum and colon. Surg Clin North Am 1969;49:381–7.

    PubMed  Google Scholar 

  2. Gunderson LL, Sosin H. Areas of failure found at reoperation (second or symptomatic look) following “curative surgery” for adenocarcinoma of the rectum. Cancer 1974;34:1278–92.

    Article  PubMed  CAS  Google Scholar 

  3. Gilbert SG. Symptomatic local tumor failure following abdominoperineal resection. Int J Radiat Oncol Biol Phys 1978;4:801–7.

    PubMed  CAS  Google Scholar 

  4. Malcolm AW, Perencevich NP, Olson RM, Hanley JA, Chaffey JT, Wilson RE. Analysis of recurrence patterns following curative resection for carcinoma of the colon and rectum. Surg Gynecol Obstet 1981;152:131–7.

    PubMed  CAS  Google Scholar 

  5. Rao AR, Kagan AR, Chan PM, Gilbert HA, Nussbaum H, Hintz BL. Patterns of recurrence following curative resection, alone for adenocarcinoma of the rectum and sigmoid colon. Cancer 1981;48:1492–5.

    Article  PubMed  CAS  Google Scholar 

  6. Walz BJ, Green MR, Lindstrom ER, Butcher HR Jr. Anatomical prognostic factors after abdominal perineal resection. Int J Radiat Oncol Biol Phys, 1981;7:477–84.

    PubMed  CAS  Google Scholar 

  7. Rosen L, Veidenheimer MC, Coller JA, Corman ML. Mortality, morbidity, and patterns of, recurrence after abdominoperineal resection for cancer of the rectum. Dis Colon Rectum 1982;25:202–8.

    Article  PubMed  CAS  Google Scholar 

  8. Mendenhall WM, Million RR, Pfaff WW. Patterns of recurrence in adenocarcinoma of the rectum and rectosigmoid treated with surgery alone: implications in treatment planning with adjuvant radiation therapy. Int J Radiat Oncol Biol Phys 1983;9:977–85.

    PubMed  CAS  Google Scholar 

  9. Pilipshen SJ, Heilweil M, Quan SH, Sternberg SS, Enker WE. Patterns of pelvic recurrence following definitive resections of rectal cancer. Cancer 1984;53:1354–62.

    Article  PubMed  CAS  Google Scholar 

  10. Pahlman L, Glimelius B. Local recurrences after surgical treatment for rectal carcinoma. Acta Chir Scand 1984;150:331–5.

    PubMed  CAS  Google Scholar 

  11. Adloff M, Arnaud JP, Schloegel M, Thibaud D. Factors influencing local recurrence after abdominoperineal resection for cancer of the rectum. Dis Colon. Rectum 1985;28:413–5.

    PubMed  CAS  Google Scholar 

  12. Mohiuddin M, Derdel J, Marks G, Kramer S. Results of adjuvant radiation therapy in cancer of the rectum: Thomas Jefferson University Hospital experience. Cancer 1985;55:350–3.

    Article  PubMed  CAS  Google Scholar 

  13. Hoskins RB, Gunderson LL, Dosoretz DE, et al. Adjuvant postoperative radiotherapy in carcinoma of the rectum and rectosigmoid. Cancer 1985;55:61–71.

    Article  PubMed  CAS  Google Scholar 

  14. Ciatto S, Pacini P. Radiation therapy of recurrences of carcinoma of the rectum and sigmoid after surgery. Acta Radiol Oncol 1982;21:105–9.

    PubMed  CAS  Google Scholar 

  15. James RD, Johnson RJ, Eddleston B, Zheng GL, Jones JM. Prognostic factors in locally recurrent rectal carcinoma treated by radiotherapy. Br J Surg 1983;70:469–72.

    PubMed  CAS  Google Scholar 

  16. Wang CC, Schutz MD. The role of radiation therapy in the management of carcinoma of the sigmoid, rectosigmoid and rectum. Radiology 1962;79:1–5.

    PubMed  CAS  Google Scholar 

  17. Welch JP, Donaldson GA. Detection and treatment of recurrent cancer of the colon and rectum. Am J Surg 1978;135:505–11.

    Article  PubMed  CAS  Google Scholar 

  18. Overgaard M, Overgaard J, Sell A. Dose-response, relationship for radiation therapy of recurrent, residual, and primarily inoperable colorectal cancer. Radiother Oncol 1984;1:217–25.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

About this article

Cite this article

Pacini, P., Cionini, L., Pirtoli, L. et al. Symptomatic recurrences of carcinoma of the rectum and sigmoid. Dis Colon Rectum 29, 865–868 (1986). https://doi.org/10.1007/BF02555365

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02555365

Key words

Navigation