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Distribution, incidence of malignant transformation, and rate of recurrence

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Diseases of the Colon & Rectum

Abstract

In 282 patients, 731 colon polyps (643 adenomas and 88 hyperplastic polyps) were extirpated endoscopically or biopsied and investigated histologically. Localization of the adenomas with various degrees of atypia and the hyperplastic polyps, as well as their size distribution, were determined. In 66 patients with adenoma polypectomy on the first examination, one or more control colonoscopies were carried out (in all, 107). The median period of follow-up observation was 31 months. Thirty percent of the one-year control colonoscopies after polypectomy revealed new adenomas. The statistical analyses showed that patients with singular adenomas, on initial investigation, develop significantly fewer adenomas in the further course than patients with multiple initial findings, especially in negative results in the one-year control. The size of new adenomas found during the first 24 months after polypectomy does not exceed 10 mm. On the basis of these results and the literature data available so far, a follow-up program is presented for discussion.

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References

  1. Stein JJ. Comments on carcinoma of the colon and rectum. Cancer 1974;34:799–800.

    Article  PubMed  Google Scholar 

  2. Hermanek P. Pathology of the adenoma-carcinoma sequence. Coloproctology 1982;4:57–64.

    Google Scholar 

  3. Rider JA, Kirsner JB, Moeller HC, Palmer WL. Polyps of the colon and rectum: their incidence and relationship to carcinoma. Am J Med 1954;16:555–64.

    Article  PubMed  CAS  Google Scholar 

  4. Wolff WI, Shinya H. Endoscopic polypectomy: therapeutic and clinicopathologic aspects. Cancer 1975;36:683–90.

    Article  Google Scholar 

  5. Williams CB, Macrae FA, Bartram CI. A prospective study of diagnostic methods in adenoma follow-up. Endoscopy 1982; 14:74–8.

    PubMed  CAS  Google Scholar 

  6. Ackroyd FW, Hedberg SE. Colonic polyps. Ann Rev Med 1985; 36:619–25.

    Article  PubMed  CAS  Google Scholar 

  7. Langer JC, Cohen Z, Taylor BR, Stafford S, Jeejeebhoy KN, Cullen JB. Management of patients with polyps containing malignancy removed by colonoscopic polypectomy. Dis Colon Rectum 1984;27:6–9.

    Article  PubMed  CAS  Google Scholar 

  8. Hermanek P, Frühmorgen P, Guggenmoos-Holzmann I, Altendorf A, Matek W. The malignant potential of colorectal polyps: a new statistical approach. Endoscopy 1983;15:16–20.

    PubMed  CAS  Google Scholar 

  9. Shinya H, Wolff WI. Morphology, anatomic distribution and cancer potential of colonic polyps: an analysis of 7,000 polyps endoscopically removed. Ann Surg 1979;190:679–83.

    PubMed  CAS  Google Scholar 

  10. Sulser H, Blöchlinger R, Nüesch HJ, Deyhle P. Klinische Pathologie der Dickdarmschleimhautpolypen. Schweiz Med Wochenschr 1979;109:1046–53.

    PubMed  CAS  Google Scholar 

  11. Webb WA, McDaniel L, Jones L. Experience with 1000 colonoscopic polypectomies. Ann Surg 1985;201:626–32.

    Article  PubMed  CAS  Google Scholar 

  12. Berges W, Brochard F, Miller B, Strohmeyer G. Neoplastische Colonpolypen. In: Frick P, von Harnack GA, Kochsiek K, Martini GA, Prader A, eds. Ergebnisse der Inneren Medizin und Kinderheilkunde. New York: Springer-Verlag, 1982.

    Google Scholar 

  13. Lipper S, Kahn LB, Ackerman LV. The significance of microscopic invasive cancer in endoscopically removed polyps of the large bowel: a clinicopathologic study of 51 cases. Cancer 1983;52:1691–9.

    Article  PubMed  CAS  Google Scholar 

  14. Muto T, Bussey HJ, Morson BC. The evolution of cancer of the colon and rectum. Cancer 1975;36:2251–70.

    PubMed  CAS  Google Scholar 

  15. Hermanek P, Giedl J. Pathologische Anatomie polypöser Prozesse im Kolon und Rektum. Leber Magen Darm 1983;13:254–60.

    PubMed  CAS  Google Scholar 

  16. Ottenjann R. Polypöse Prozesse im Kolon und Rektum. Leber Magen Darm 1983;13:251–3.

    PubMed  CAS  Google Scholar 

  17. Matek W, Guggenmoos-Holzmann I, Demling L. Follow-up of patients with colorectal adenomas. Endoscopy 1985;17:175–81.

    PubMed  CAS  Google Scholar 

  18. Feczko PJ, Bernstein MA, Halpert RD, Ackerman LV. Small colonic polyps: a reappraisal of their significance. Radiology 1984;152:301–3.

    PubMed  CAS  Google Scholar 

  19. Granqvist S, Gabrielsson N, Sundelin P. Diminutive colonic polyps: clinical significance and management. Endoscopy 1979; 1:36–42.

    Google Scholar 

  20. Tedesco FJ, Hendrix JC, Pickens CA, Brady PG, Mills LR. Diminutive polyps: histopathology, spatial distribution, and clinical significance. Gastrointest Endosc 1982;28:1–5.

    PubMed  CAS  Google Scholar 

  21. Fowler DL, Hedberg SE. Follow-up colonoscopy after polypectomy. Gastrointest Endosc 1980;26:67.

    Google Scholar 

  22. Neugut AI, Johnsen CM, Forde KA, Treat MR. Recurrence rates for colorectal polyps. Cancer 1985;55:1586–9.

    Article  PubMed  CAS  Google Scholar 

  23. Waye JD, Braunfeld S. Surveillance intervals after colonoscopic polypectomy. Endoscopy 1982;14:79–81.

    Article  PubMed  CAS  Google Scholar 

  24. Minopoulos GJ, McIntyre RL, Lee EC, Kettlewell MG. Colonoscopic polypectomy in a regional teaching hospital. Br J Surg 1983;70:51–3.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Medicine St. Josef Hospital, Ruhr University, Gudrunstr. 56, D-4630, Bochum, West Germany

    Martin Wegener M.D., Gereon Börsch M.D. & Gabriele Schmidt M.D.

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  1. Martin Wegener M.D.
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  2. Gereon Börsch M.D.
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  3. Gabriele Schmidt M.D.
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Wegener, M., Börsch, G. & Schmidt, G. Distribution, incidence of malignant transformation, and rate of recurrence. Dis Colon Rectum 29, 383–387 (1986). https://doi.org/10.1007/BF02555053

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  • DOI: https://doi.org/10.1007/BF02555053

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