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Metachronous colorectal cancer

Time interval to presentation of a metachronous cancer

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Diseases of the Colon & Rectum

Abstract

A retrospective review of 1888 colorectal cancer patients demonstrated 37 metachronous cancers in 30 patients for a metachronous cancer rate of 1.6 percent. Evaluation of the index cancers consisted of the traditional single-contrast barium enema and proctoscopic evaluation. Forty percent of the metachronous cancers appeared within two years of the index cancer. If the minimum length of the polyp-cancer sequence is three to five years, then this represents a failure of a traditional preoperative evaluation. A more sensitive evaluation potentially could decrease the metachronous cancer rate. Colonoscopy, which has been found to be more accurate in detecting synchronous neoplasms, should be included in the evaluation of all patients with colorectal cancers.

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References

  1. Warren S, Gates O. Multiple primary malignancy tumors: a survey of the literature and a statistical study. Am J Cancer 1932;16:1358–1414.

    Google Scholar 

  2. Travieso CR Jr, Knoepp LF Jr, Hanley PH. Multiple adenocarcinomas of the colon and rectum. Dis Colon Rectum 1972;15:1–6.

    PubMed  Google Scholar 

  3. Kaibara N, Koga S, Jinnai D. Synchronous and metachronous malignancies of the colon and rectum in Japan with special reference to a coexisting early cancer. Cancer 1984;54:1870–4.

    Article  PubMed  CAS  Google Scholar 

  4. Ginzburg L, Dreiling DA. Successive independent (metachronous) carcinomas of the colon. Ann Surg 1956;143:117–20.

    Article  PubMed  CAS  Google Scholar 

  5. Heald RJ, Lockhart-Mummery HE. The lesion of the second cancer of the large bowel. Br J Surg 1972;59:16–9.

    PubMed  CAS  Google Scholar 

  6. Törnqvist A, Ekelund G, Leandoer L. Early diagnosis of metachronous colorectal carcinoma. Aust NZ J Surg 1981;51:442–5.

    Google Scholar 

  7. Moertel CG, Bargen JA, Dockerty MB. Multiple carcinomas of the large intestine: a review of the literature and a study of 261 cases. Gastroenterology 1958;34:85–98.

    PubMed  CAS  Google Scholar 

  8. Spratt JS Jr, Hoag MG. Incidence of multiple primary cancers per man-year of follow up: 20-year review from the Ellis Fischel State Cancer Hospital. Ann Surg 1966;164:775–84.

    Article  PubMed  Google Scholar 

  9. Muto T, Bussey HJ, Morson BC. The evolution of cancer of the colon and rectum. Cancer 1975;36:2251–70.

    PubMed  CAS  Google Scholar 

  10. Agrez MV, Ready R, Ilstrup D, Beart RW Jr. Metachronous colorectal malignancies. Dis Colon Rectum 1982;25:569–74.

    Article  PubMed  CAS  Google Scholar 

  11. Long JW, Mayo CW, Dockerty MB, Judd ES Jr. Recurrent versus new and independent carcinomas of the colon and rectum. Mayo Clin Proc 1950;25:169–78.

    PubMed  CAS  Google Scholar 

  12. Weir JA. Cancer of the colon in South Saskatchewan: a population study. Cancer 1973;31:616–20.

    Article  PubMed  CAS  Google Scholar 

  13. Burns FJ. Synchronous and metachronous malignancies of the colon and rectum. Dis Colon Rectum 1980;23:578–9.

    Article  PubMed  CAS  Google Scholar 

  14. Langevin JM, Nivatvongs S. The true incidence of synchronous cancer of the large bowel: a prospective study. Am J Surg 1984;147:330–3.

    Article  PubMed  CAS  Google Scholar 

  15. Reilly JC, Rusin LC, Theuerkauf FJ Jr. Colonoscopy: its role in cancer of the colon and rectum. Dis Colon Rectum 1982;25:532–8.

    PubMed  CAS  Google Scholar 

  16. Heald RJ, Bussey MJ. Clinical experiences at St. Mark's Hospital with multiple synchronous cancers of the colon and rectum. Dis Colon Rectum 1975;18:6–10.

    PubMed  CAS  Google Scholar 

  17. Pagana TJ, Ledesma EJ, Mittelman A, Nava HR. The use of colonoscopy in the study of synchronous colorectal neoplasms. Cancer 1984;53:356–9.

    Article  PubMed  CAS  Google Scholar 

  18. Thorson AG, Davis SJ, Christensen MA. The role of colonscopy in the preoperative assessment of patients with colorectal cancer. Dis Colon Rectum (In press.)

  19. Gilbertsen VA. Proctosigmoidoscopy and polypectomy in reducing the incidence of rectal cancer. Cancer 1974;34:936–9.

    Article  PubMed  Google Scholar 

  20. Prager ED, Swinton NW, Young JL, Veidenheimer MC, Corman ML. Follow-up study of patients with benign mucosal polyps discovered by proctosigmoidoscopy. Dis Colon Rectum 1974;17:322–4.

    PubMed  CAS  Google Scholar 

  21. Maxfield RG. Colonoscopy as a routine preoperative procedure for carcinoma of the colon. Am J Surg 1984;147:477–80.

    Article  PubMed  CAS  Google Scholar 

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Read at the meeting of the American Society of Colon and Rectal Surgeons, San Diego, California, May 5 to 10, 1985.

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Kiefer, P.J., Thorson, A.G. & Christensen, M.A. Metachronous colorectal cancer. Dis Colon Rectum 29, 378–382 (1986). https://doi.org/10.1007/BF02555051

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  • DOI: https://doi.org/10.1007/BF02555051

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