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Diverticular disease of the large bowel in Singapore

An autopsy survey

  • Published:
Diseases of the Colon & Rectum


One thousand fourteen consecutive large intestines were removed at autopsy from persons over the age of 14 years and examined for diverticular disease. Diverticulosis was encountered in 194 patients (19 percent). The lesion appeared early in life, after the second decade. Men were affected more frequently than women before the age of 60 years. Chinese men had significantly more diverticular disease than Malayan men (P<0.01) and Indian men (P<0.02). Chinese men also had significantly more diverticular disease than Chinese women. There was a predominance of right colon involvement, with the disease affecting especially the ascending colon and cecum. This pattern was observed in all three major ethnic groups, and in both the Singapore-born and foreign-born Singaporeans. The cause of right-sided diverticulosis is unknown. It appears that, while adoption of the western diet may influence the prevalence of diverticular disease, the site of predilection is determined more by racial or genetic predisposition. All diverticular examined histologically were false, including 39 (20 percent) solitary diverticula. The distribution of solitary diverticula was similar to that of multiple diverticulosis. It is suggested that solitary and multiple diverticulosis are part of the spectrum of the same disease.

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  1. Painter NS. Diverticular disease of the colon: a disease of this century. Lancet 1969;2:586–8.

    Article  PubMed  CAS  Google Scholar 

  2. Painter NS, Burkitt DP. Diverticular disease of the colon: a deficiency disease of western civilization. Br Med J 1971;2:450–4.

    Article  PubMed  CAS  Google Scholar 

  3. Stemmermann GN, Yatani R. Diverticulosis and polyps of the large intestine: a necropsy study of Hawaii Japanese. Cancer 1973;31:1260–70.

    Article  PubMed  CAS  Google Scholar 

  4. Segal I, Solomon A, Hunt JA. Emergence of diverticular disease in the urban South African black. Gastroenterology 1977;72:215–9.

    PubMed  CAS  Google Scholar 

  5. Burkitt DP. Epidemiology of cancer of the colon and rectum. Cancer 1971;28:3–13.

    Article  PubMed  CAS  Google Scholar 

  6. Shanmugaratnam K, Lee HP, Day NE. Cancer incidence in Singapore 1968–1977. IARC Scientific Publications No. 47, 1983.

  7. Kyle J, Adesola AO, Tinckler LF, de Beaux J. Incidence of diverticulitis. Scand J Gastroenterol 1967;2:77–80.

    Article  CAS  PubMed  Google Scholar 

  8. Tan LK. The prevalence and pattern of diverticular disease in Singapore population. Galloway lecture delivered at combined medical meeting Singapore, 1981.

  9. Tan EC, Tung KH, Tan L, Wee A. Diverticulitis of caecum and ascending colon in Singapore. J R Coll Surg Edinb 1984;29:373–6.

    PubMed  CAS  Google Scholar 

  10. Williams PL, Warwick R, eds. Gray's anatomy. Philadelphia: WB Saunders, 1980:1350–1356.

    Google Scholar 

  11. Manousos O, Day NE, Tzonou A, et al. Diet and other factors in the aetiology of diverticulosis: an epidemiological study in Greece. Gut 1985;26:544–9.

    PubMed  CAS  Google Scholar 

  12. Peck DA, Labat R, Waite VC. Diverticular disease of the right colon. Dis Colon Rectum 1968;11:49–54.

    PubMed  CAS  Google Scholar 

  13. Hughes LE. Postmortem survey of diverticular disease of the colon. Gut 1969;10:336–51.

    PubMed  CAS  Google Scholar 

  14. Chang WY. Colonic diverticulosis in Hawaii: a study of 414 cases. Hawaii Med J 1965;24:442–5.

    PubMed  CAS  Google Scholar 

  15. Vajrabukka T, Saksornchai K, Jimakorn P. Diverticular disease of the colon in a far-eastern community. Dis Colon Rectum 1980;23:151–4.

    PubMed  CAS  Google Scholar 

  16. Morson BC. The muscle abnormality in diverticular disease of the sigmoid colon. Br J Radiol 1963;36:385–92.

    Article  Google Scholar 

  17. Murayama N, Baba S, Kodaida S, Abe O. An aetiological study of diverticulosis of the right colon. Aust NZ J Surg 1981;51:420–5.

    CAS  Google Scholar 

  18. Sugihara K, Muto T, Morioka Y. Motility study in right sided diverticular disease of the colon. Gut 1983;24:1130–4.

    PubMed  CAS  Google Scholar 

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Lee, YS. Diverticular disease of the large bowel in Singapore. Dis Colon Rectum 29, 330–335 (1986).

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