Abstract
In a prospective trial, the resection margins of 130 patients who underwent apparently curative resection for colorectal cancers were examined. Sialomucin was markedly increased in 17.0 percent of proximal resection margins and 17.3 percent in distal resection margins. Clinical follow-up has demonstrated four patients who have developed local recurrence of their disease. Three of these patients had increased sialomucin staining in the resection margins at the time of initial surgery. High iron diamine-alcian blue staining of resection margin may identify those patients at risk of developing local recurrence of colorectal cancer or metachronous tumor following apparently curative resection.
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Supported by the Cancer Research Council of the United Kingdom.
Read at the joint meeting of the American Society of Colon and Rectal Surgeons with the Section of Colo-Proctology, Royal Society of Medicine, and the Section of Colonic and Rectal Surgery, Royal Australasian College of Surgeons, New Orleans, Louisiana, May 6 to 11, 1984.
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Wood, C.B., Dawson, P.M. & Habib, N.A. The sialomucin content of colonic resection margins. Dis Colon Rectum 28, 260–261 (1985). https://doi.org/10.1007/BF02554047
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DOI: https://doi.org/10.1007/BF02554047