Skip to main content

Advertisement

SpringerLink
Log in

Estrogen and progestin receptors in colonic cancer?

  • Published:
Diseases of the Colon & Rectum

Abstract

Adenocarcinomas of the large bowel in 28 consecutive patients were examined for the presence of estrogen and progestin receptor proteins. None of the specimens showed specific high affinity receptor binding. Our findings suggest that adenocarcinoma of the large bowel does not contain cytoplasmic receptor sites for estrogen and progestin.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Alford TC, Do HM, Geelhoed GW, et al. Steroid hormone receptors in human colon cancers. Cancer 1979;43:980–4.

    Article  PubMed  CAS  Google Scholar 

  2. Sica V, Papaleo G, Nola E, et al. Estrogen and progesterone receptors in colorectal cancer. In: Periti P., Grassi G, eds. Current chemotherapy and immunotherapy. Washington DC, Am Soc Microbiol, 1981;1564–6.

    Google Scholar 

  3. Stedman KE, Moore GE, Morgan RT. Estrogen receptor proteins in diverse human tumors. Arch Surg 1980;115:244–8.

    PubMed  CAS  Google Scholar 

  4. Zhu NY, Cai XH, Wu LL, Zou R. Determination of estrogen receptor in human colon cancer tissue with labeled fluorescence estradiol (fluorescein isothiocyanaat). Chin Med J 1981;94: 607–10.

    PubMed  CAS  Google Scholar 

  5. Agrez MV, Spencer RJ. Estrogen receptor protein in adenomas of the large bowel. Dis Colon Rectum 1982;25:348–50.

    Article  PubMed  CAS  Google Scholar 

  6. Panettiere FJ, Timothy T. SWOG trial of tamoxifen in patients with advanced colorectal cancinoma. ASCO Abstracts 1982;C 364, 94.

    Google Scholar 

  7. EORTC Breast Cancer Cooperative Group. Revision of the standards for the assessment of hormone receptors in human breast cancer. Eur J Cancer 1980;16:1513–5.

    Google Scholar 

  8. Bucci L, Salfi R, Meraviglia F, Delrio G. Hormonal receptors in colorectal cancers. Abstract 2nd European Conference on Clinical Oncology and Cancer Nursing 1983;8:41–98.

    Google Scholar 

  9. McClendon JE, Appleby D, Claudon DB, et al. Colonic neoplasms, tissue estrogen receptor and carcinoembryonic antigen. Arch Surg 1977;112:140–241.

    Google Scholar 

  10. Koenders AM, Thorpe SM (on behalf of the EORTC Receptor Group). Standardization of steroid receptor analysis in human breast cancer. Eur J Cancer Clin Oncol 1983;19:1221–2.

    Article  PubMed  CAS  Google Scholar 

  11. Koenders T, Benraad TJ (on behalf of the participating laboraties). Quality control of estrogen receptor assays in the Netherlands. Breast Cancer Res Treatment 1983;255–66.

Download references

Author information

Authors and Affiliations

  1. Department of General Surgery and the Departments of Medicine, Division of Endocrinology, and Experimental and Chemical Endocrinology, St. Radboud University Hospital, Nijmegen, The Netherlands

    Th. Wobbes M.D., L. V. A. M. Beex M.D. & A. M. J. Koenders Ph.D.

Authors
  1. Th. Wobbes M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. V. A. M. Beex M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. M. J. Koenders Ph.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

No reprints will be available.

About this article

Cite this article

Wobbes, T., Beex, L.V.A.M. & Koenders, A.M.J. Estrogen and progestin receptors in colonic cancer?. Dis Colon Rectum 27, 591–592 (1984). https://doi.org/10.1007/BF02553846

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02553846

Key words

Search

Navigation