Summary
In 1,076 women the forearm bone mineral content (BMC) had been measured with single photon gamma absorptiometry (SPA) 10–16 years ago. The incidence of fractures incurred in the ensuing years (1975–1985) was recorded. The BMC had been significantly less in those women who were to have the types of fractures that are related to bone fragility but only in women measured during the first post-menopausal decades. From age 50–69, diminished BMC at the distal forearm site was associated with a threefold increase of relative risk whereas at the proximal site there was about a sixfold increase in relative risk. This association was not evident in the pppulation over 70 years of age because of a high frequency of fractures (mostly of the spine) in subjects with relatively high BMC values. Body weight and grip strength were significantly lower in the fracture group over 70 years of age
Similar content being viewed by others
References
Nilsson BE, Westlin NE (1977) Bone mineral content and fragility fractures. Clin Orthop 125:196–199
Finn Jensen G, Christiansen C, Boesen J, Hegedüs V, Transböl I (1983) Relationship between bone mineral content and frequency of postmenopausal fractures. Acta Med Scand 213:61–63
Wasnich RD, Ross PD, Heibrun LK, Vogel JM (1985) Prediction of postmenopausal fracture risk with use of bone mineral measurements. Am J Obstet Gynecol 153:745–751
Melton LJ, Wahner HW, Richelson LS, O'Fallon WM, Riggs BL (1986) Osteoporosis and the risk of hip fracture. A J Epidemol 124:254–261
Nordin BEC, Polley K (1987) Metabolic consequences of the menopause. A cross-sectional, longitudinal, and intervention study on 557 normal postmenopausal women. Calcif Tissue Int (Suppl 1, Vol 41)
Wasnich RD, Ross PD, Heilbrun LK, Vogel JM (1987) Selection of the optimal skeletal site for fracture risk prediction. Clin Orthop 216:262–269
Ross PD, Wasnich RD, Heilbrun LK, Vogel JM (1987) Definition of a spine fracture threshold based upon prospective fracture risk. Bone 8:271–278
Ross PD, Wasnich RD, Vogel JM (1988) Detection of prefracture spinal osteoporosis using bone mineral absorptiometry. J Bone Min Res 3:1–11
Melton LJ III, Wahner HW, Riggs BL (1988) Bone density measurement (Editorial). J Bone Min Res 3:ix-x
Naclér LOW, Nilsson BE, Westlin NE (1974) An apparatur for gamma absorptiometry of bone—technical data. Opuscula Medicotechnica 12
Johnell O, Nilsson BE (1985) Hip fracture and accident disposition. Acta Orthop Scand 56:302–304
Aniansson A, Zetterberg C, Hedberg M, Henriksson KG (1984) Impaired muscle function with aging. Clin Orthop 191:193–201
Johnell O, Sernbo I (1986) Health and social status in patients with hip fractures and controls. Age and Ageing 15:285–291
Lindsay R, Dempster DW, Clemens T, Herrington BS, Wilt S (1984) Incidence, cost, and risk factors of fracture of the proximal femur in the U.S.A. Osteoporosis. Proc Copenhagen Int Symp on Osteoporosis, June 3–8, 311–315
Juel Riis B, Rödbro P, Christiansen C (1986) The role of serum concentrations of sex steroids and bone turnover in the development and occurrence of postmenopausal osteoporosis. Calcif Tissue Int 38:318–322
Riggs BL, Melton LJ, Wahner HW (1983) Heterogeneity of involutional osteoporosis: evidence for two distinct osteoporosis syndrome. In: Frame B, Potts JT Jr (eds) Clinical Disorders of bone and mineral metabolism. Exerpta Medica, Amsterdam 337–342
Christiansen C, Gotfredsen A, Nillas L, Riis BJ, Thomsen K (1986) Spontaneous and oestrogen-caused bone changes in early postmenopausal women: a local or generalized phenomenon? XIX Eur Symp on Calcif Tissues, Stockholm, Sweden, June 15–19
Aloia JF, Vaswani A, Ellis K, Yuen K, Cohn SH (1985) A model for involutional bone loss. J Lab Clin Med 106:630–637
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gärdsell, P., Johnell, O. & Nilsson, B.E. Predicting fractures in women by using forearm bone densitometry. Calcif Tissue Int 44, 235–242 (1989). https://doi.org/10.1007/BF02553757
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF02553757