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Septicemia in surgical patients with intestinal diseases

  • Published:
Diseases of the Colon & Rectum

Summary

A study was undertaken to define the microbiologic spectrum of septicemia in surgical patients with intestinal diseases, to learn more about its clinical manifestations, and to determine factors related to its pathogenesis and outcome. During a 2 1/2-year period we detected and treated septicemia in 27 patients, of whom ten died. Results indicated that septicemia was caused by a wide variety of opportunistic bacteria or fungi and was produced by infections in a number of anatomic locations. Underlying noninfectious diseases, especially severe malnutrition and cachexia secondary to intestinal conditions and intractable renal failure, often were important determinants of a fatal outcome of infection. Early manifestations of septicemia frequently were subtle, atypical, or mistaken for expressions of other illnesses. The urinary or respiratory tracts and indwelling intravenous catheters served as apparent portals of entry for septicemia in a sizable proportion of the patients; adoption of additional preventive measures for those types of hospital-acquired infections, hopefully, may further reduce the low incidence of septicemia in our patients in the future.

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References

  1. Altemeier, W. A., J.C. Todd and W. W. Inge: Gram-negative septicemia: A growing threat. Ann. Surg.166: 530, 1967.

    Article  PubMed  CAS  Google Scholar 

  2. Corso, J. A., R. Agostinelli and M. W. Brandriss: Maintenance of venous polyethylene catheters to reduce risk of infection. J.A.M.A.210: 2075, 1969.

    PubMed  CAS  Google Scholar 

  3. Gotsman, M. S. and J. L. Whitby: Respiratory infection following tracheostomy. Thorax19: 89, 1964.

    Article  PubMed  CAS  Google Scholar 

  4. Kunin, C. M. and R. C. McCormack: Prevention of catheter-induced urinary-tract infections by sterile closed drainage. New Eng. J. Med.274: 1156, 1966.

    Google Scholar 

  5. Martin, C. M., F. Vaquer, M. S. Myers, and A. El-Dadah: Prevention of gram-negative rod bacteremia complicating indwelling urinary tract catheterization. In Kass, E. H. (editor): Progress in Pyelonephritis. Philadelphia, F. A. Davis Co., 1965, pp. 692–703.

    Google Scholar 

  6. McHenry, M. C.: Bacteremic shock due to gram-negative bacilli: Some concepts of pathogenesis and management based on recent developments. Geriatrics24: 101 (Apr.) 1969.

    PubMed  CAS  Google Scholar 

  7. McHenry, M. C. and R. B. Turnbull, Jr.: Early presumptive antibacterial therapy for potentially fatal infections in surgical patients with intestinal diseases. Proc. Roy. Soc. Med.63 (Suppl.): 25–28, 1970.

    PubMed  Google Scholar 

  8. Pierce, A. K., J. P. Sanford, G. D. Thomas, and J. S. Leonard: Long-term evaluation of decontamination of inhalation-therapy equipment and the occurrence of necrotizing pneumonia. New Eng. J. Med.282: 528, 1970.

    Article  PubMed  CAS  Google Scholar 

  9. Rosebury, T.: Microorganisms Indigenous to Man. New York, Blakiston Division, McGraw-Hill Book Company, Inc., 1962, 435 pp.

    Google Scholar 

  10. Weil, M. H., H. Shubin, and M. Biddle: Shock caused by gram-negative microorganisms: Analysis of 1969 cases. Ann. Intern. Med.60: 384, 1964.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Internal Medicine, Section of Infectious Disease, The Cleveland Clinic Foundation, Cleveland, Ohio

    Martin C. McHenry M.D., Rupert B. Turnbull Jr. M.D., Frank L. Weakley M.D. & William A. Hawk M.D.

  2. The Department of Colon and Rectal Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio

    Martin C. McHenry M.D., Rupert B. Turnbull Jr. M.D., Frank L. Weakley M.D. & William A. Hawk M.D.

  3. Department of Pathology, The Cleveland Clinic Foundation, Cleveland, Ohio

    Martin C. McHenry M.D., Rupert B. Turnbull Jr. M.D., Frank L. Weakley M.D. & William A. Hawk M.D.

Authors
  1. Martin C. McHenry M.D.
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  2. Rupert B. Turnbull Jr. M.D.
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  3. Frank L. Weakley M.D.
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  4. William A. Hawk M.D.
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Additional information

Read at the Meeting of the American Proctologic Society, Hollywood, Florida, April 12 to 16, 1970.

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McHenry, M.C., Turnbull, R.B., Weakley, F.L. et al. Septicemia in surgical patients with intestinal diseases. Dis Colon Rectum 14, 195–199 (1971). https://doi.org/10.1007/BF02553185

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  • DOI: https://doi.org/10.1007/BF02553185

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