Abstract
Androgen, progesterone and estrogen receptors were analyzed in 12 primary colonic cancers and 16 primary rectal cancers. Androgen and progesterone receptors were positive in some colonic cancers and rectal carcinomas; however, none of the specimens analyzed showed estradiol receptor.
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References
King RJ, Mainwaring WI. Steroid cell interactions. Baltimore: University Park Press, 1974.
O'Malley BW, Birnbaumer L. Receptors and hormone action. New York: Academic Press, 1978:2.
Hamilton TH, Clark JH, Sadler WA. Ontogeny of receptors and reproductive hormone action. New York: Raven Press, 1979.
Leavitt WW, Clark JH, eds. Steroid hormone receptor systems. New York: Plenum Press, 1978.
Litwack G, ed. Biochemical actions of hormones. New York: Academic Press, 1979.
Lippman ME, Huff K. A demonstration of androgen and estrogen receptors in human breast cancer using a new protamine sulfate assay. Cancer 1976;38:868–74.
McGuire WL, Horwitz KB, Pearson OH, Segaloff A. Current status of estrogen and progesterone receptors in breast cancer. Cancer 1977;39:2934–47.
Fazekas AG, MacFarlane JK. Macromolecular binding of glucocorticoids in human mammary carcinoma. Cancer Res 1977;37:640–5.
Burke RE, McGuire WL. Nuclear thyroid receptors in a human breast cancer cell line. Cancer Res 1978;38:3769–73.
McGuire WL, Carbone PP, Vollmer EP. Estrogen receptors in human breast cancer. New York: Raven Press, 1975.
Hsu RS. Androgen receptors in human prostates. In: Normal and abnormal growth of the prostate. Springfield: Charles C Thomas, 1975:663–75.
Lippman ME, Halterman RH, Leventhal BG, Perry S, Thompson EB. Glucocorticoid-binding proteins in human acute lymphoblastic leukemic blast cells. J Clin Invest 1973;52:1715–25.
Stedman KE, Moore GE, Morgan RT. Estrogen receptor proteins in diverse human tumors. Arch Surg 1980;115:244–8.
Alford TC, Do HM, Geelhoed GW, Tsangaris NT, Lippman ME. Steroid hormone receptors in human colon cancers. Cancer 1979;43:980–4.
Sica V, Papaleo G, Nola E, et al. Estrogen and progesterone receptors in colorectal cancer. In: Periti P, Grassi G, eds. Current chemotherapy and immunotherapy. Washington: American Society of Microbiology, 1981:1564–6.
Agrez MV, Spencer RJ. Estrogen receptor protein in adenomas of the large bowel. Dis Colon Rectum 1982;25:348–50.
McClendon JE, Appleby D, Claudon DB, Donegan WL, DeCosse JJ. Colonic neoplasms: tissue estrogen receptor and carcinoembryonic antigen. Arch Surg 1977;112:240–1.
Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248–54.
Ekman P, Barrack ER, Walsh PC. Simultaneous measurement of progesterone and androgen receptors in human prostate: a microassay. J Clin Endocrinol Metab 1982;55:1089–99.
Wobbes T, Beex LV, Koenders AM. Estrogen and progestin receptors in colonic cancer? Dis Colon Rectum 1984;27:591–2.
Clark GM, McGuire WL, Hubay CA, Pearson OH, Marshall JS. Progesterone receptors as a prognostic factor in stage II breast cancer. N Engl J Med 1983;309:1343–7.
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This research was performed under CNR Project “Controllo della Crescita Neoplastica”.
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d'Istria, M., Fasano, S., Catuogno, F. et al. Androgen and progesterone receptors in colonic and rectal cancers. Dis Colon Rectum 29, 263–265 (1986). https://doi.org/10.1007/BF02553034
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DOI: https://doi.org/10.1007/BF02553034