Abstract
A case is described in which flow cytometric DNA analysis of a sigmoid cancer and a subsequently diagnosed anal malignancy demonstrated the same DNA aneuploid pattern in both tumors. The ability to show, by this technique of DNA analysis, that an anal malignancy has seeded from a colon cancer could be important for future therapy. This is because the positive identification of such a deposit as a “dropped” metastasis would prevent inappropriately radical surgery.
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Scott, N.A., Taylor, B.A., Wolff, B.G. et al. Perianal metastasis from a sigmoid carcinoma—Objective evidence of a clonal origin. Dis Colon Rectum 31, 68–70 (1988). https://doi.org/10.1007/BF02552574
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DOI: https://doi.org/10.1007/BF02552574