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The efficacy of urinary cytology in the detection of recurrent bladder tumours

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Abstract

In a prospective study, 71 patients with superficial transitional cell carcinoma of the bladder were given topical immunotherapy with bacillus Calmette-Guerin after transurethral resection and the impact of cystoscopy and bladder wash-out cytology in assessment of recurrent tumours was investigated. Sixteen recurrences were noted histopathologically during the follow-up and 15 of them were also diagnosed properly by wash-out cytology (sensitivity 93.8%). During the follow-up, 10 patients had positive cytology results without evidence of recurrent tumour and 6 of them had recurred cystoscopically in 3 months' time. However, the remaining 4 patients were still tumour-free cystoscopically after a follow-up of 6 months (specificity 92.7%, positive predictive value 78.9%). Although, some false-positive results may be obtained by urine cytology after topical immunotherapy, urine cytology seems to be a reasonable alternative to more invasive and expensive methods during the follow-up of bladder tumours.

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Authors and Affiliations

  1. Department of Urology, Ankara University, Ibn-i Sina Hospital, Ankara, Turkey

    S. Baltaci, O. Süzer, G. Özer, Y. Bedük & O. Göĝüş

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  1. S. Baltaci
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  2. O. Süzer
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  3. G. Özer
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  4. Y. Bedük
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  5. O. Göĝüş
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Baltaci, S., Süzer, O., Özer, G. et al. The efficacy of urinary cytology in the detection of recurrent bladder tumours. International Urology and Nephrology 28, 649–653 (1996). https://doi.org/10.1007/BF02552160

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  • DOI: https://doi.org/10.1007/BF02552160

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