Abstract
Fifty impotent patients have been evaluated with intracorporeal injection of papaverine and colour Doppler ultrasound. The papaverine tests were negative in 34 of 50 patients. Nineteen of 34 patients with negative papaverine results showed normal colour Doppler findings. In 14 of 16 patients with positive papaverine results the colour Doppler analysis revealed normal structure and functions. Correlation between intracorporeal papaverine injection and colour Doppler ultrasound results was found in 59% (p<0.01). We concluded that intracorporeal papaverine injection is an effective, simple diagnostic test for beginning evaluation of impotent men. However, this screening test should be supported by colour Doppler ultrasound.
Similar content being viewed by others
References
Newman, H. F., Northup, J. D.: Mechanism of human penile erection: An overview.Urology, 17, 359 (1981).
Wespes, E., Schulman, C. C.: Venous leakage: Surgical treatment of a curable cause of impotence.J. Urol., 133, 796 (1985).
Lue, T. F., Zeineh, S. O., Schimidt, R. A., Tanagho, E. A.: Neuroanatomy of penile erection: Its recurrence to iatrogenic impotence.J. Urol., 131, 273 (1984).
Lue, T. F., Tanagho, E. A.: Physiology of erection and pharmacological management of impotence.J. Urol., 137, 829 (1987).
Lincoln, J., Crowe, R., Backlay, P. F., Pryor, J. P., Lumley, J. S. P., Burnstock, G.: Changes in VIPergic, cholinergic and adrenergic innervation of human penile tissue in diabetic and non-diabetic males.J. Urol., 137, 1053 (1987).
Benson, G. S.: Penile erection in search of a neutrotransmitter.World J. Urol., 1, 209 (1983).
Virag, R.: Intracavernous injection of papaverine for erectile failure.Lancet, 2, 938 (1982).
Virag, R., Friedman, V., Legman, M., Virag, H.: Intracavernous injection of papaverine as a diagnostic and therapeutic method in erectile failure.Angiology, 35, 79 (1984).
Barry, J. M., Hodges, C. V.: Impotence: A diagnostic approach.J. Urol., 119, 575 (1978).
Azadoi, K. M., Goldstein, I.: Atherosclerosis induced corporeal leakage impotence.Surg. Forum, 38, 647 (1987).
Wespes, E., Bulcous C: The erectile angle, objective criteria to evaluate the papaverine test in impotence.J. Urol., 138, 1171 (1987).
Lue, T. F., Hricak, H., Manich, K. W.: Vasculogenic impotence evaluated by high-resolution ultrasonography and pulsed Doppler spectrum analysis.Radiology, 155, 777 (1985).
Chiang, P. H., Chiang, C. P., Wu, C. L., Wang, C. J., Chen, M. T., Huang, C. H., Wu, D. K.: Colour duplex sonography in the assessment of impotence.Br. J. Urol., 68, 181 (1991).
Schwartz, A. N., Wang, K. Y., Mack, L. A., Lowe, M., Berger, R. E., Cry, D. R., Feldman, M.: Evaluation of normal erectile function with color flow Doppler sonography.A.J.R., 153, 1155 (1989).
Hampson, S. J., Cowie, A. G. A., Rickards, D., Lees, W. R.: Independent evaluation of impotence by color Doppler imaging and cavernosometry.Bur. Urol., 21, 27 (1992).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Çetinkaya, M., Erdoĝan, E., Adsan, Ö. et al. Evaluation of impotent men with intracorporeal injection of papaverine and colour doppler ultrasound. International Urology and Nephrology 27, 779–782 (1995). https://doi.org/10.1007/BF02552147
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02552147