Abstract
Pituitary and gonadal functions in 16 prepubertal boys with chordee without hypospadias by stimulation of gonadotropin releasing hormone or human chorionic gonadotropin were compared to those of age-matched normal boys. The patients with chordee without hypospadias had poor follicular stimulating hormone response but pituitary luteinizing hormone reserve function was normal.
Testosterone response by stimulation of human chorionic gonadotropin was not impaired in patients with chordee without hypospadias. The results suggested that chordee without hypospadias may also be categorized into hypospadias from the aspect of its pituitary and gonadal functions in addition to the embryogenesis of chordee.
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Culp, O. S.: Struggles and triumphs with hypospadias and associated anomalies: review of 400 cases.J. Urol., 96, 339 (1966).
Kramer, S. A., Aydin, G., Kelalis, P. P.: Chordee without hypospadias in children.J. Urol., 128, 559 (1982).
Shima, H., Ikoma, F., Terakawa, T., Satoh, Y., Nagata, H., Shimada, K., Nagano, S.: Developmental anomalies associated with hypospadias.J. Urol., 122, 619 (1979).
Okuyama, A., Namiki, M., Koide, T., Itatani, H., Nishimoto, N., Mizutani, S., Sonoda, T., Aono, T., Matsumoto, K.: Pituitary and gonadal function in prepubertal and pubertal boys with hypospadias.Acta Endocrinol., 98, 464 (1981).
Nonomura, K., Fujita, K., Sakakibara, N., Terasawa, K., Matsuno, T., Matsumura, N., Koyanagi, T.: Pituitary and gonadal function in prepubertal boys with hypospadias.J. Urol., 132, 595 (1984).
Shima, H., Ikoma, F., Yabumoto, H., Mori, M., Satoh, Y., Terakawa, T., Fukuchi, M.: Gonadotropin and testosterone response in prepubertal boys with hypospadias.J. Urol., 135, 539 (1986).
Hamilton, W. J., Mossman, H. W.: Human Embryology. Williams and Wilkins Co., Baltimore 1972, pp. 377–436.
Imperato-McGinly, J., Peterson, R. E.: Male pseudohermaphroditism: The complexities of male phenotypic development.Am. J. Med., 61, 251 (1976).
Glenister, T. W.: The origin and fate of the urethral plate in man.J. Anat., 88, 413 (1954).
Devine, C. J., Horton, C. E.: Chordee without hypospadias.J. Urol., 110, 264 (1973)
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Shima, H., Okamoto, E. & Ikoma, F. Pituitary and gonadal functions in patients with chordee without hypospadias. International Urology and Nephrology 24, 69–73 (1992). https://doi.org/10.1007/BF02552120
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DOI: https://doi.org/10.1007/BF02552120