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Myocardial scintigraphy with infarct-avid tracers

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References

  1. Holman, B.L., Eldh, P., Adams, D.F., Han, M.H., Poggenburg, J.K., Adelstein, S.J.: Evaluation of myocardial perfusion after intracoronary injection of radiopotassium. J. Nucl. Med. 14:274–278 1973

    PubMed  CAS  Google Scholar 

  2. Evans, J.R., Gunton, R.W., Baker, R.G., Beanlands, D.S., Spears, J.C.: Use of radioiodinated fatty acid for photoscans of the heart. Circ. Res. 16:1–10 1965

    PubMed  CAS  Google Scholar 

  3. Strauss, H.W., Zaret, B.L., Martin, N.D., Wells, H.P., Jr., Flamm, M.D., Jr.: Noninvasive evaluation of regional myocardial perfusion with potassium 43. Technique in patients with exercise-induced transient myocardial ischemia. Radiology 108:85–90, 1973

    PubMed  CAS  Google Scholar 

  4. Holman, B.L., Dewanjee, M.K., Idoine, J., Fliegel, C.P., Davis, M.A., Treves, S., Eldh, P., Detection and localization of experimental myocardial infarction with99m-Tc-tetracycline. J. Nucl. Med. 14:595–599, 1973

    PubMed  CAS  Google Scholar 

  5. Holman, B.L., Lesch, M., Zweiman, F.G., Temte, J., Lown, B., Gorlin, R.: Detection and sizing of acute myocardial infarcts with99mTc(Sn)tetracycline. N. Engl. J. Med. 291:159–163, 1974

    Article  PubMed  CAS  Google Scholar 

  6. Holman, B.L., Tanaka, T.T., Lesch, M.: Evaluation of radiopharmaceuticals for the detection of acute myocardial infarction in man. Radiology 121:427–430, 1976

    PubMed  CAS  Google Scholar 

  7. Parkey, R.W., Bonte, F.J., Meyer, S.L., Atkins, J.M., Curry, G.L., Stokely, E.M., Willerson, J.T.: A new method for radionuclide imaging of acute myocardial infarction in humans. Circulation 50:540–546, 1974

    PubMed  CAS  Google Scholar 

  8. Bonte, F.J., Parkey, R.W., Graham, K.D., Moore, J., Stokely, E.M.: A new method for radionuclide imaging of myocardial infarcts. Radiology 110:473–474, 1974

    PubMed  CAS  Google Scholar 

  9. Zaret, B.L., DiCola, V.C., Donabedian, R.K., Puri, S., Wolfson, S., Freedman, G.S., Cohen, L.S.: Dual radionuclide study of myocardial infarction. Relationships between myocardial uptake of potassium-43, technetium-99m stannous pyrophosphate, regional myocardial blood flow and creatine phosphokinase depletion. Circulation 53:422–428, 1976

    PubMed  CAS  Google Scholar 

  10. Shen, A.C., Jennings, R.B.: Myocardial calcium and magnesium in acute ischemic injury. Am. J. Pathol. 67:417–440, 1972

    PubMed  CAS  Google Scholar 

  11. Buja, L.M., Tofe, A.J., Mukherjee, A., Parkey, R.W., Bonte, F.J., Willerson, J.T.: Role of elevated tissue calcium in myocardial infarct scintigraphy with technetium phosphorous radiopharmaceuticals. Circulation (Suppl.) 54:II-219, 1976

    Google Scholar 

  12. Dewanjee, M.K.: Localization of skeletal-imaging99mTc chelates in dead cells in tissue culture: Concise communication. J. Nucl. Med. 17:993–997, 1976

    PubMed  CAS  Google Scholar 

  13. Schelbert, H., Ingwall, J., Sybers, H., Ashburn, W.: Uptake of Tc-99m pyrophosphate and calcium in irreversibly damaged myocardium. J. Nucl. Med. 17:534, 1976

    Google Scholar 

  14. Holman, B.L., Chisholm, R.J., Braunwald, E.: The prognostic implications of acute myocardial infaret scintigraphy with99mTc-pyrophosphate. Circulation 57:320–326, 1978.

    PubMed  CAS  Google Scholar 

  15. Parkey, R.W., Bonte, F.J., Stockely, E.M., Meyer, A.L., Willerson, J.T.: Analysis of Tc-99m stannous pyrophosphate myocardial scintigrams in 242 patients. J. Nucl. Med. 16:556, 1975

    Google Scholar 

  16. Ennis, J.T., Walsh, M.J., Mahon, J.M.: Value of infarct-specific isotope (99mTc-labelled stannous pyrophosphate) in myocardial scanning. Br. Med. J. 3:517–520, 1975

    PubMed  CAS  Google Scholar 

  17. Karunaratne, H.B., Walsh, W.F., Fill, H.R., Resnekov, L., Harper, P.V.: Technetium-99m pyrophosphate myocardial scintigraphy in patients with chest pain—lack of diagnostic specificity. J. Nucl. Med. 17:523–524, 1976

    Google Scholar 

  18. Cowley, M.J., Mantle, J.A., Rogers, W.J., Russell, R.O. Jr., Rackley, C.E., Logic, J.R.: Technetium-99m stannous pyrophosphate myocardial scintigraphy. Reliability and limitations in assessment of acute myocardial infarction. Circulation 56:192–198, 1977

    PubMed  CAS  Google Scholar 

  19. Walsh, W.F., Karunaratne, H.B., Resnekov, L., Fill, H.R., Harper, P.V.: Assessment of diagnostic value of technetium-99m pyrophosphate myocardial scintigraphy in 80 patients with possible acute myocardial infarction. Br. Heart J. 39:974–981, 1977

    PubMed  CAS  Google Scholar 

  20. Holman, B.L., Lesch, M., Alpert, J.S.: Myocardial scintigraphy with technetium-99m pyrophosphate during the early phase of acute infarction. Am. J. Cardiol. 41:39–42, 1978

    Article  PubMed  CAS  Google Scholar 

  21. Olson, H.G., Lyons, K.P., Aronow, W.S., Brown, W.T., Greenfield, R.S.: Follow-up technetium-99m stannous pyrophosphate myocardial scintigrams after acute myocardial infarction. Circulation 56:181–187, 1977

    PubMed  CAS  Google Scholar 

  22. Buja, L.M., Poliner, L.R., Parkey, R.W., Pulido, J.I., Hutcheson, D., Platt, M.R., Mills, L.J., Bonte, F.J., Willerson, J.T.: Clincopathologic study of persistently positive technetium-99m stannous pyrophosphate myocardial seintigrams and myocytolytic degeneration after myocardial infarction. Circulation 56:1016–1023, 1977

    PubMed  CAS  Google Scholar 

  23. Ahmad, M., Dubiel, J., Verdon, T.A., Martin, R.H.: Technetium-99m stannous pyrophosphate myocardial imaging in patients with left ventricular aneurysm. Clin. Res. 23:168a, 1975

    Google Scholar 

  24. Walsh, W., Lessem, J., Fill, H., Harper, P.V. Value of99mTc-pyrophosphate myocardial scintigraphy in patients with suspected myocardial infarction. Am. J. Cardiol. 37:180, 1976

    Article  Google Scholar 

  25. Holman, B.L.: Radionuclide methods in the evaluation of myocardial ischemia and infarction. Circulation (Suppl.) 53:I—112—119, 1976

    Google Scholar 

  26. Pugh, B.R., Buja, L.M., Parkey, R.W., Poliner, L.R., Stokely, E.M., Bonte, F.J., Willerson, J.T.: Cardioversion and “false positive” technetium-99m stannous pyrophosphate myocardial scintigrams. Circulation 54:399–403, 1976

    PubMed  CAS  Google Scholar 

  27. Go, R.T., Chiu, C.L., Doty, D.B., Cheng, H.F., Christie, J.H.: Radionuclide imaging of experimental myocardial contusion. J. Nucl. Med. 15:1174–1175, 1974

    PubMed  CAS  Google Scholar 

  28. Serafini, A.N., Raskin, M.M., Zand, L.C., Watson, D.D.: Radionuclide breast scanning in carcinoma of the breast, J. Nucl. Med. 15:1149–1152, 1974

    PubMed  CAS  Google Scholar 

  29. Chacko, A.K., Gordon, D.H., Bennett, J.M., O'Mara, R.E., Wilson, G.A.: Myocardial imaging with Tc-99m pyrophosphate in patients on adriamycin treatment for neoplasia. J. Nucl. Med. 18:680–683, 1977

    PubMed  CAS  Google Scholar 

  30. Klein, M.S., Coleman, R.E., Roberts, R., Weiss, A.N.:99mTc(Sn)pyrophosphate scintigrams in exercise-induced angina and calcified valves. Am. J. Cardiol. 37:149, 1976

    Article  Google Scholar 

  31. Jengo, J.A., Mena, I., Joe, S.H., Criley, J.M.: The significance of calcific valvular heart disease in Tc-99m pyrophosphate myocardial infarction scanning: Radiographic, scintigraphic, and pathological correlation. J. Nucl. Med. 18:776–780, 1977

    PubMed  CAS  Google Scholar 

  32. Bossuyt, A., Verbeelen, D.: Accumulation of99mTc pyrophosphate in the skin lesions of pseudoxanthoma elasticum. Clin. Nucl. Med. 1:245, 1976

    Article  Google Scholar 

  33. Hisada, K., Suzuki, Y., Iimori, M.: Technetium-99m pyrophosphate bone imaging in the evaluation of trauma. Clin. Nucl. Med. 1:18–25, 1976

    Article  Google Scholar 

  34. Rosenthall, L., Hill, R.O., Chuang, S.: Observation on the use of99mTc-phosphate imaging in peripheral bone trauma. Radiology 119:637, 1976

    PubMed  CAS  Google Scholar 

  35. Kim, E.: Calcified costal cartilage as a cause of false interpretation on myocardial imaging. Clin. Nucl. Med. 1:159–161, 1976

    Article  Google Scholar 

  36. Klein, M.S., Coleman, R.E., Roberts, R., Weiss, A.N.: False positive99mTc(Sn)pyrophosphate myocardial infarct images related to delayed blood pool clearance. Clin. Nucl. Med. 1:45–47, 1976

    Article  Google Scholar 

  37. Prasquier, R., Taradash, M.R., Botvinick, E.H., Shames, D.M., Parmley, W.W.: The specificity of the diffuse pattern of cardiac uptake in myocardial infarction imaging with technetium-99m stannous pyrophosphate. Circulation 55:61–66, 1977

    PubMed  CAS  Google Scholar 

  38. Donsky, M.S., Curry, G.C., Parkey, R.W., Meyer, S.L., Bonte, F.J., Platt, M.R., Willerson, J.T.: Unstable angina pectoris. Clinical, angiographic, and myocardial scintigraphic observations Br. Heart J. 38:257–263, 1976

    PubMed  CAS  Google Scholar 

  39. Abdulla, A.M., Canedo, M.I., Cortez, B.C., McGinnis, K.D., Wilhelm, S.K.: Detection of unstable angina by99mtechnetium pyrophosphate myocardial scintigraphy. Chest 69:168–173, 1976

    PubMed  CAS  Google Scholar 

  40. Perez, L.A., Hayt, D.B., Freeman, L.M.: Localization of myocardial disorders other than infarction with99mTc-labeled phosphate agents. J. Nucl. Med. 17:241–246, 1976

    PubMed  CAS  Google Scholar 

  41. Willerson, J.T., Parkey, R.W., Buja, L.M., Harris, R.A., Jr., Stokely, E.M., Blomqvist, G., Bonte, F.J.: Sizing acute myocardial infarction utilizing technetium stannous pyrophosphate myocardial scintigrams in dogs and man. Circulation 52 (Suppl.) 52:I-108, 1975

    Google Scholar 

  42. Stokely, E.M., Buja, L.M., Lewis, S.E., Parkey, R.W., Bonte, F.J., Harris, R.A., Jr., Willerson, J.T.: Measurement of acute myocardial infarcts in dogs with99mTc-stannous pyrophosphate scintigrams. J. Nucl. Med. 17:1–5, 1976

    PubMed  CAS  Google Scholar 

  43. Botvinick, E.H., Shames, D., Lappin, H., Tyberg, J.V., Townsend, R., Parmely, W.W.: Noninvasive quantitation of myocardial infarction with technetium-99m pyrophosphate. Circulation 52:909–915, 1975

    PubMed  CAS  Google Scholar 

  44. Holman, B.L., Ehrie, M., Lesch, M.: Correlation of acute myocardial infarct scintigraphy with postmortem studies. Am. J. Cardiol. 37:311–313, 1976

    Article  PubMed  CAS  Google Scholar 

  45. Henning, H., Schelbert, H., O'Rourke, R.A., Righetti, A., Hardarson, T., Ashburn, W.: Dual myocardial imaging with Tc-99m pyrophosphate and thallium-201 for diagnosing and sizing acute myocardial infarction. J. Nucl. Med. 17:524, 1976

    Google Scholar 

  46. Keyes, J.W., Leonard, P.F., Brody, S.L., Svetkoff, D.J., Rogers, W.L., Lucchest, B.R.: Myocardial infaret quantification in the dog by single photon emission computed tomography. Circulation 58:227–232, 1978

    PubMed  CAS  Google Scholar 

  47. Sharpe, D.N., Botvinick, E.H., Shames, D.M., Schiller, N.B., Massie, B.M., Chatterjee, K., Parnley, W.W.: The noninvasive diagnosis of right ventricular infarction. Circulation 57:483–490, 1978

    PubMed  CAS  Google Scholar 

  48. Righetti, A., O'Rourke, R.A., Schelbert, H., Henning, H., Hardarson, T., Daily, P.O., Ashburn, W., Ross, J., Jr.: Usefulness of preoperative and postoperative Tc-99m(Sn)pyrophosphate scans in patients with ischemic and valvular heart disease. Am. J. Cardiol. 39:43–49, 1977

    Article  PubMed  CAS  Google Scholar 

  49. Platt, M.R., Parkey, R.W., Willerson J.T., Bonte, F.J., Shapiro, W., Sugg, W.L., Technetium stannous pyrophosphate myocardial scintigrams in the recognition of myocardial infarction in patients undergoing coronary artery revascularization. Ann. Thorac. Surg. 21:311–317, 1976

    Article  PubMed  CAS  Google Scholar 

  50. Fink-Bennett, D., Dworkin, H.J., Lee, Y.H.: Myocardial imaging of the acute infarct. Radiology 113:449–450, 1974

    PubMed  CAS  Google Scholar 

  51. Rossman, D.J., Rouleau, J., Strauss, H.W., Pitt, B.: Detection and size estimation of acute myocardial infarction using99mTc-glucopheptonate, J. Nucl. Med. 16:980–985, 1975

    PubMed  CAS  Google Scholar 

  52. Khaw, B.A., Beller, G.A., Haber, E.: Experimental myocardial infarct imaging following intravenous administration of iodine-131 labeled antibody (Fab′)2 fragments specific for cardiac myosin. Circulation 57:743–750, 1978

    PubMed  CAS  Google Scholar 

  53. Davis, M.A., Holman, B.I., Carmel, A.N.: Evaluation of radiopharmaceuticals sequestered by acutely damaged myocardium. J. Nucl. Med. 17:911–917, 1976

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA

    B. L. Holman M.D. & J. Wynne

  2. Department of Radiology, Harvard Medical School, 25 Shattuck Street, 02115, Boston, MA, USA

    B. L. Holman M.D. & J. Wynne

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Supported in part by USPHS grant HL 17739. Dr. Holman is an Established Investigator of the American Heart Association

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Holman, B.L., Wynne, J. Myocardial scintigraphy with infarct-avid tracers. Cardiovasc Radiol 2, 175–182 (1979). https://doi.org/10.1007/BF02552062

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