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Enzyme changes after coronary angiography

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Abstract

The enzymatic response to contrast media after coronary angiography was observed in 24 patients. The enzymes studied were glutamic oxaloacetic transaminase (SGOT), glutamic pyruvic transaminase (SGPT), lactic dehydrogenase (LDH), α-hydroxybutyrate dehydrogenase (α-HBDH), γ-glutamyl transferase (γ-GT), creatine phosphokinase (CPK), and the myocardial-specific isoenzyme of CPK (CK-MB). Angiography produced no significant elevations in SGOT, SGPT, α-HBDH, LDH, or CK-MB activities; γ-GT increased up to the twelfth hour. High levels of CPK and CK-MB observed in one patient were found to be products of a thymus carcinoma. In vitro examinations also showed that concentrations of contrast media used in coronary angiography do not inhibit γ-GT, LDH, and CPK activities.

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Authors and Affiliations

  1. Department of Cardiology, Medical Clinic of the Waldkrankenhaus Erlangen, Rathsbergerstr. 57, D-8520, Erlangen, FRG

    A. Weikl, M. Hubmann, O. E. Durst & E. Lang

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  1. A. Weikl
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  2. M. Hubmann
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  3. O. E. Durst
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  4. E. Lang
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Weikl, A., Hubmann, M., Durst, O.E. et al. Enzyme changes after coronary angiography. Cardiovasc Radiol 1, 153–156 (1978). https://doi.org/10.1007/BF02552026

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