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Peyronie's disease: Intralesional treatment with interferon alpha-2A and evaluation of the results by magnetic resonance imaging

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Abstract

In this clinical study, to determine the therapeutic efficacy of interferon (IFN) treatment for Peyronie's disease, we applied interferon alpha-2A (IFN alpha-2A) intralesionally in the treatment of Peyronie plaques in 15 patients and results were evaluated by magnetic resonance imaging (MRI).

Patients whose plaque sizes were 0.5 and 1 cm responded better to the treatment. There was about a 90% lessening in the sizes of the plaques of 1.5 cm, 83.3% of 2 cm, as the ones which were 0.5 cm and 1 cm disappeared completely after treatment.

As a conclusion, the treatment of Peyronie's disease with IFN alpha-2A is effective and side effects are minimum.

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Authors and Affiliations

  1. Department of Urology, Atatürk University School of Medicine, Erzurum, Turkey

    Ö. Polat, O. Gül & I. Özbey

  2. Department of Radiology, Atatürk University School of Medicine, Erzurum, Turkey

    M. Özdikici & Y. Bayraktar

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  1. Ö. Polat
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  2. O. Gül
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  3. I. Özbey
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  4. M. Özdikici
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  5. Y. Bayraktar
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Polat, Ö., Gül, O., Özbey, I. et al. Peyronie's disease: Intralesional treatment with interferon alpha-2A and evaluation of the results by magnetic resonance imaging. International Urology and Nephrology 29, 465–471 (1997). https://doi.org/10.1007/BF02551115

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