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Cytophotometric investigations on a chronic tubular nephropathy simulating preneoplastic condition

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Abstract

Cytophotometric investigations were performed on the atypical renal tubular epithelium of a young man who died of renal failure, possibly due to chronic lead exposure. The aim of this analysis was to determine whether nuclear atypia indicates incipient malignancy or is a type of so-called “benign atypias”. DNA histogram, showing euployd polyploidy supports the latter view and the dysplastic epithelial lesion is not even considered to be a preneoplastic condition.

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Authors and Affiliations

  1. Department of Pathology, County Hospital Szolnok, Pécs, Hungary

    P. Károlyi

  2. Department of Pathology, County Hospital, Pécs, Hungary

    G. Hegedüs

  3. Oncopathological Research Institute, Budapest, Hungary

    Z. Szentirmay

  4. University Medical School, Pécs, Hungary

    G. Deák

Authors
  1. P. Károlyi
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  2. G. Hegedüs
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  3. Z. Szentirmay
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  4. G. Deák
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Károlyi, P., Hegedüs, G., Szentirmay, Z. et al. Cytophotometric investigations on a chronic tubular nephropathy simulating preneoplastic condition. International Urology and Nephrology 21, 211–216 (1989). https://doi.org/10.1007/BF02550810

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  • DOI: https://doi.org/10.1007/BF02550810

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