Abstract
To study the development of new scars and progression of previous scarring, we analysed 711 children with primary VUR. New scar or progression of previous scarring was observed in 7.3% of the kidneys with reflux. Factors which promote the formation of new scars are high-grade VUR, recurrent UTIs and high-pressure bladder which results in high-pressure reflux. The average age of new scarring was from 7 to 9 years. We emphasize the importance of the follow-up study until the age of 15 years, even after reflux has stopped following surgery.
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Bellinger, M. F.: The management of vesicoureteric reflux.Urol. Clin. North Am., 12, 23 (1985).
Filly, R., Friedland, G. W., Govan, D. E., Fair, W. R.: Development and progression of clubbing and scarring in children with recurrent urinary tract infections.Radiology, 113, 145 (1974).
Winter, A. L., Hardy, B. E., Alton, D. J., Arbus, G. S., Churchill, B. M.: Acquired renal scars in children.J. Urol., 129, 1190 (1983).
Shah, K. J., Robins, D. G., White, R. H.: Renal scarring and vesicoureteric reflux.Arch. Dis. Child., 53, 210 (1978).
Cardiff-Oxford Bacteriuria Study Group: Sequelae of covert bacteriuria in schoolgirls. A four-year follow up study.Lancet, 1, 889 (1978).
Smelle J. M., Ransley, P. G., Normand, I. C. S., Prescod, N., Edwards, D.: Development of new renal scars; a collaborative study.Br. Med. J., 290, 1957 (1985).
Lyon, R. P., Smith, D. R.: Distal urethral stenosis.J. Urol., 89, 414 (1963).
Allen, T. D.: Vesicoureteral reflux and the unstable bladder (Editorial).J. Urol., 134, 1180 (1985).
King, L. R.: Sphincter dyssynergia in children with reflux.J. Urol., 129, 217 (1983).
Ikoma, F., Shimada, K.: Clinical experience of reflux nephropathy. In: Murakami, K., Kitagawa, T., Yabuta, K., Sakai, T. (eds): Recent Advances in Pediatric Nephrology. Proceedings of the 7th International Congress of Pediatric Nephrology. Elsevier Science Publishers, Amsterdam 1987.
Lenaghan, D., Whitaker, J. C., Jensen, F., Stephens, F. D.: The natural history of reflux and long-term effects of reflux on the kidney.J. Urol., 115, 728 (1976).
McLachlan, M. S. F., Meller, S., Verrier-Jones, E. R., Asscher, A. W., Fletcher, E. W. L., Mayon-White, R. T., Ledingham, J. G. S., Smith, J. C., Johnston, H. H.: Urinary tract in schoolgirls with covert bacteriuria.Arch. Dis. Child., 50, 253 (1975).
Edwards, D., Normand, I. C. S., Prescod, N., Smellie, J. M.: Disappearance of vesicoureteric reflux during long-term prophylaxis of urinary tract infection in children.Br. Med. J., 2, 285 (1977).
Elo, J., Tallgren, L. G., Alfthan, O., Sarna, S.: Character of urinary tract infections and pyelonephritic renal scarring after antireflux surgery.J. Urol., 129, 343 (1983).
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Shimada, K., Matsui, T., Ogino, T. et al. New development and progression of renal scarring in children with primary VUR. International Urology and Nephrology 21, 153–158 (1989). https://doi.org/10.1007/BF02550803
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DOI: https://doi.org/10.1007/BF02550803