Abstract
In order to investigate the effect of triathlon and renal function of normal subjects, we evaluated the excretion of urinary enzymes and proteins before and after triathlon. From 6 subjects samples were obtained 24 hours after the first urine collection. We performed quantification of urinary total protein, β2-microglobulin (β2-M), N-acetyl-β-D-glucosaminidase activity (NAG), and concentration of urinary creatinine from each participant. There was a significant increase in urinary total protein excretion immediately after triathlon (p<0.01). The urinary β2-M and NAG excretions after triathlon were higher than the initial values. Post-exercise proteinuria in one subject persisted until the next morning, whereas the increased excretion of urinary β2-M and NAG returned to the pre-exercise level at least 24 hours after triathlon. It appears to be reasonable to presume that glomerular damage may persist in some subjects who do heavy exercise.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Campanacci, L., Faccini, L., Englaro, E., Rusti, R., Guanieri, G. F., Barat, R., Carraro, M., De Zotti, R., Micheli, W.: Exercise-induced proteinuria.Contr. Nephrol., 26, 31 (1981).
Carlier, B., Ninane, G., Joris, G.: Specificity of urinary N-acetyl-D-glucosaminidase.Lancet, 264 (1979).
Castenfors, J.: Renal function during prolonged exercise.Ann. N. Y. Acad. Sci., 301, 151 (1977).
Cosenzi, A., Carraro, M., Sacerdote, A., Franca, G., Plemontesi, A., Bocin, E., Faccini, L., Bellini, G.: Involvement of the renin angiotensin system in the pathogenesis of postexercise proteinuria.Scand. J. Urol. Nephrol., 27, 301 (1993).
Gardner, K. D.: Athletic pseudonephritis—Alteration of urinary sediment by athletic competition.J. Amer. Med. Assoc., 161, 1613 (1956).
Khoury, G., Hopper, J. C., Varghese, B. Z.: Nephrotoxicity of ionic and non-ionic material in digital vascular imaging and selective renal angiography.Br. J. Radiol., 56, 631 (1983).
Ohno, H., Yamashita, H., Ookawara, T., Kizaki, T., Sato, Y., Taniguchi, N.: Effect of physical exercise on urinary excretion of CuZn-superoxide dismutase in male high school students.Acta Physiol. Scand., 148, 353 (1993).
Poortmans, J. R.: Postexercise proteinuria in humans: Facts and mechanisms.J. Amer. Med. Assoc., 253, 236 (1985).
Priest, J. B., Oei, T. O., Moorehead, W. R.: Exercise-induced changes in common laboratory tests.Amer. J. Clin. Pathol., 77, 285 (1982).
Refsum, H. E., Stromme, S. B.: Renal osmol clearance during prolonged heavy exercise.Scand. J. Clin. Lab. Invest., 38, 19 (1977).
Schwab, S. J., Christensen, R. L., Dougherty, K., Klahr, S.: Quantitation of proteinuria by the use of protein-to-creatinine ratios in single urine samples.Arch. Intern. Med., 147, 943 (1987).
Wellwood, J. M., Ellis, B. G., Price, R. G., Hammond, K., Thompson, A. E., Jones, N. F.: Urinary N-acetyl-b-glucosaminidase activities in patients with renal disease.Br. Med. J., 16, 408 (1975).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Yaguchi, H., Ishigooka, M., Hayami, S. et al. The effect of triathlon on urinary excretion of enzymes and proteins. International Urology and Nephrology 30, 107–112 (1998). https://doi.org/10.1007/BF02550562
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02550562