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Failure of blood pressure control by a new combined alpha-and beta-blocking agent (amosulalol) in a patient with pheochromocytoma

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Abstract

A 42-year-old woman with pheochromocytoma received preoperatively a combined alpha-and beta-adrenoceptor blocking agent, amosulalol, exerting some inhibitory action on both receptors. Severe hypertension and remarkable fluctuation of heart rate occurred following this medication. Although it is claimed currently that a combined blocking agent is useful for the management of this disease, it should be administered with caution.

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Authors and Affiliations

  1. Department of Urology, School of Medicine, Yamagata University, Yamagata, Japan

    T. Yamaguchi, C. Irisawa, H. Watanabe, S. Kawamura & T. Nakada

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  1. T. Yamaguchi
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  2. C. Irisawa
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  3. H. Watanabe
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  4. S. Kawamura
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  5. T. Nakada
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Yamaguchi, T., Irisawa, C., Watanabe, H. et al. Failure of blood pressure control by a new combined alpha-and beta-blocking agent (amosulalol) in a patient with pheochromocytoma. International Urology and Nephrology 23, 209–214 (1991). https://doi.org/10.1007/BF02550413

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  • DOI: https://doi.org/10.1007/BF02550413

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