Abstract
A hypothesis is presented that microorganisms at very high concentration (>1010/ml) interfere with the sperm-egg interaction by masking the equatorial fibronectin band (EFB) of human sperm and thus impair the fertilization process.
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Akiyama, S. K., Yamada, K. M.: Fibronectin in disease. In: B. Wagner, R. Fleischmajer, N. Kaufmann (eds): Connective Tissue Diseases. Williams & Wilkins, Baltimore 1982, pp. 55–96.
Bedford, J. M., Moore, H. D. M., Franklin, L. E.: Significance of the equatorial segment of the acrosome of the spermatozoa in eutherian mammals.Exp. Cell Res., 119, 119 (1979).
Glander, H. J., Herrmann K., Haustein, U. F.: The equatorial fibronectin band (EFB) on human spermatozoa—a diagnostic help for male fertility?Andrologia, 19, 456 (1987).
Glander, H. J., Schönborn, Ch., Rytter, M.: Microbiological investigations on cryopreserved human semen.Int. J. Androl., 6, 358 (1983).
Grizard, G., Janny, L., Hermabessiere, J., Sirot, J., Boucher, D.: Seminal biochemistry and sperm characteristics in infertile men with bacteria in ejaculate.Arch. Androl., 15, 181 (1985).
Guillet-Rosso, F., Pari, A., Taylor, S., Forman, R., Belaisch-Allart, J., Testart, J., Frydman, R.: Systematic semen culture and its influence in IVF management.Br. J. Obstet. Gynaecol., 94, 543 (1985).
Hewitt, H. J., Cohen, J., Fehilly, C. B.: Seminal bacterial pathogens and in vitro fertilization.J. In Vitro Fert. Embryo Transfer, 2, 105 (1985).
Klebe, R. J.: Isolation of a collagen-dependent cell attachment factor.Nature, 250, 248 (1974).
Kuusela, P.: Fibronectin binds to Staphylococcus aureus.Nature, 276, 718 (1978).
Mc Gowan, M. P., Burger, H. G., Baker, H. W., de Krestern, D. M., Kovacs, G.: The incidence of non specific infection in the semen of infertile and subfertile males.Int. J. Androl., 4, 657 (1981).
Toth, A., Lessel, M. L.: Asymptomatic bacteriospermia in fertile and infertile men.Fertil. Steril., 36, 881 (1981).
WHO-Laboratory Manual for the Examination of Human Semen and Semen Cervical Mucus Interaction. Cambridge University Press, Cambridge-New York-New Rochelle-Melbourne-Sydney 1987.
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Glander, H.J., Herrmann, K. & Haustein, U.F. Impairment of the fertilization process by adherence of microorganism to the equatorial fibronectin band (EFB) of human sperm. International Urology and Nephrology 22, 483–486 (1990). https://doi.org/10.1007/BF02549782
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DOI: https://doi.org/10.1007/BF02549782