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Prolactin secretion in kidney transplant patients

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Abstract

In 27 male patients with a functioning kidney transplant and in 12 healthy male subjects plasma prolactin levels were estimated under baseline, inhibitory and stimulatory conditions, respectively. Kidney transplant patients (KTP) showed normal base-line plasma levels of prolactin, and a normal response of prolactinaemia to α-bromocriptine. In contrast, administration of chlorpromazine was followed by an exaggerated response of prolactin secretion in KTP as compared with normals. Type of immunosuppressive therapy (cyclosporine A or azathioprine) did not influence significantly the plasma prolactin profile in KTP under either inhibitory or stimulatory conditions.

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Authors and Affiliations

  1. Department of Nephrology, Silesian School of Medicine, Katowice, Poland

    W. Grzeszczak, F. Kokot, A. Wi⊹cek & E. Żukowska-Szczechowska

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  1. W. Grzeszczak
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  2. F. Kokot
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  3. A. Wi⊹cek
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  4. E. Żukowska-Szczechowska
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Additional information

This work was supported by the Polish Ministry of Health and Welfare, MZ XIII.

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Grzeszczak, W., Kokot, F., Wi⊹cek, A. et al. Prolactin secretion in kidney transplant patients. International Urology and Nephrology 22, 567–571 (1990). https://doi.org/10.1007/BF02549746

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  • DOI: https://doi.org/10.1007/BF02549746

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