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The pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis

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Abstract

Twenty-six patients with unilateral and bilateral hydronephrosis were subjected to investigation to identify the patterns of PRA-aldosterone system. The incidence of hypertension in the unilateral group was 28.5%, while in the bilateral group it was 50%; the overall incidence was 34.6%. In the hypertensive patients (9 cases), plasma renin activity and aldosterone were normal in one, and elevated in three. Aldosterone only was elevated in 3 cases, while PRA was elevated in 2. In the normotensive patients, the levels of PRA and aldosterone were normal in 5 patients, while in the remaining 12 cases one or both parameters were elevated.

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References

  1. Andaloro, V. A. Jr.: Mechanism of hypertension produced by ureteral obstruction.Urology, 5, 367 (1975).

    Article  Google Scholar 

  2. Belman, A. B., Kropp, K. A., Simon, N. M.: Renal pressor hypertension secondary to unilateral hydronephrosis.N. Engl. J. Med., 278, 1133 (1968).

    Article  PubMed  CAS  Google Scholar 

  3. Braasch, W. F., Walters, W., Hammer, H. J.: Hypertension and the surgical kidney.JAMA, 155, 1837 (1940).

    Google Scholar 

  4. Carelin, J. A.: Hyperreninaemia in an infant secondary to pelviureteric obstruction treated successfully by surgery.J. Pediatr., 88, 987 (1976).

    Article  Google Scholar 

  5. Fitz, A.: Renal venous renin determination in the diagnosis of surgically corrected hypertension.Circulation, 36, 942 (1967).

    PubMed  CAS  Google Scholar 

  6. Franklin, S., Merrill, J. P.: The kidney in health, the nephron in disease.Am. J. Med., 28, 1 (1960).

    Article  PubMed  CAS  Google Scholar 

  7. Gunnells, J. C. Jr., McGuffin, W. L. Jr., Robinson, R. R.: Peripheral and renal venous plasma renin activity in hypertension.Ann. Intern Med., 71, 555 (1969).

    PubMed  Google Scholar 

  8. Kyunpark, M., Juichi Kawa Mura, Osamuyoshida, D.: Hypertension with elevated renal vein renin secondary to unilateral hydronephrosis.Urology, 16, 499 (1980).

    Article  Google Scholar 

  9. Palmer, J. M., Zweiman, F. G., Assaykeen, T. A.: Renal hypertension due to hydronephrosis with normal plasma activity.N. Engl. J. Med., 283, 1032 (1970).

    Article  PubMed  CAS  Google Scholar 

  10. Weidmann, P., Piccoli, C. D., Hirsch, D., Reubi, F. C., Massry, S. G.: Curable hypertension with unilateral hydronephrosis; studies on the role of circulating renin.Ann. Intern. Med., 87, 437 (1977).

    PubMed  CAS  Google Scholar 

  11. Platts, M. M.: Renal function in patients with unilateral hydronephrosis.Br. Med. J., 5367, 1243 (1963).

    Article  Google Scholar 

  12. Strauss M. B., Welt, L.: Diseases of the Kidney. Second edition. Little Brown and Co., Boston 1971, Vol. II, p. 1011.

    Google Scholar 

  13. Rao, M. R., Heptinstall, R. H.: Experimental hydronephrosis: a microangiographic study.Invest. Urol., 6, 183 (1968).

    PubMed  CAS  Google Scholar 

  14. Robert, A., Riehle, J. K., Darracott, E., Vaughan, E. D. Jr.: Renin participation in hypertension associated with unilateral hydronephrosis.J. Urol., 126, 243 (1981).

    Google Scholar 

  15. Salvetti, A.: The relationship between P.R.A. and daily rate of urinary sodium excretion in normal subjects.J. Nucl. Biol. Med., 18, 119 (1974).

    PubMed  CAS  Google Scholar 

  16. Savage, J. M., Dillon, M. J., Shah, V., Barratt, T. M., Williams, D. I.: Renin and blood pressure in children with renal scarring and vesico-ureteric reflux.Lancet, II, 441 (1978).

    Article  Google Scholar 

  17. Schiff, M. Jr., McGuire, E. J., Baskin, A. M.: Hypertension and unilateral hydronephrosis.Urology, 5, 178 (1975).

    Article  PubMed  Google Scholar 

  18. Schwartz, D. T.: Unilateral upper urinary tract obstruction and arterial hypertension.N. Y. J. Med., 69, 668 (1969).

    CAS  Google Scholar 

  19. Squitier, A. P., Ceccarell, F. E., Wurster, J. C.: Hypertension with elevated renal vein renin secondary to ureteropelvic junction obstruction.J. Urol., 111, 284 (1974).

    Google Scholar 

  20. Sukiw, E.: Pattern of nephron perfusion in acute and chronic hydronephrosis.J. Clin. Invest., 45, 122 (1966).

    Article  Google Scholar 

  21. Vaughan, E. D. J. R., Sweet, R. C., Gillenwater, J. Y.: Peripheral renin and blood pressure changes following complete unilateral ureteral occlusion.J. Urol. 104, 89 (1970).

    PubMed  Google Scholar 

  22. Vaughan, E. D. Jr., Buhler, F. R., Laragh, J. H.: Normal renin secretion in hypertensive patient with primarily unilateral chronic hydronephrosis.J. Urol., 112, 153 (1974).

    PubMed  Google Scholar 

  23. Vaughan, E. D. Jr.: Hypertension and unilateral parenchymal renal disease.JAMA, 223, 1117 (1975).

    Google Scholar 

  24. Wise, H. M.: Hypertension resulting from hydronephrosis.JAMA, 231, 491 (1975).

    Article  PubMed  Google Scholar 

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  1. Department of Urology, Faculty of Medicine, Ain Shams University, Abbassia, Cairo, Egypt

    M. Ezzat I

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  1. M. Ezzat I
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Ezzat, M. The pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis. International Urology and Nephrology 19, 55–63 (1987). https://doi.org/10.1007/BF02549678

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  • DOI: https://doi.org/10.1007/BF02549678

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