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A study of possible causal relations between squamous cell carcinoma of the penis and carcinoma of the cervix uteri

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Abstract

The authors investigated 26 regular sexual female partners of 24 men with squamous cell carcinoma of the penis. Neoplasms were diagnosed in 6 (23.1%) of the total of 26 women. STDs were found in 6 (23.1%) women. In 2 the cytologic findings on the cervix were classified as PAP III (PAP IIIa—CIN I, PAP IIIb—CIN III). Squamous cell carcinoma of the uterine cervix was found in 2 women (1 case PAP IV—CIN III; 1 case PAP V—suggestive of invasive carcinoma). Endometrial adenoacanthoma, mammary adenocarcinoma, squamous cell carcinoma of the right hand and non-Hodgkin's malignant lymphoma (centroblastic) were found in 1 case each.

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References

  1. Allen, D. W., Cole, P.: Viruses and human cancer.N. Engl. J. Med., 286, 70 (1972).

    Article  PubMed  CAS  Google Scholar 

  2. Beral, V.: Cancer of the cervix: A sexually transmitted infection?Lancet, 1, 1037 (1974).

    Article  PubMed  CAS  Google Scholar 

  3. Buckley, J. D., Doll, R., Harris, R. W. C., Vessey, M. P., Wiliams, P. T.: Case-control study of the husbands of women with dysplasia or carcinoma of the cervix uteri.Lancet, 2, 1010 (1981).

    Article  PubMed  CAS  Google Scholar 

  4. Clarke, E. A., Morgan, R. W., Newman, A. M.: Smoking as a risk factor in cancer of the cervix: Additional evidence from a case-control study.Am. J. Epidemiol., 115, 59 (1982).

    PubMed  CAS  Google Scholar 

  5. Fu, Y. S., Beaudenon, S., Ionesco, M., Barrasso, R., Brux, J., Orth, G.: Correlative study of human papillomavirus DNA, histopathology, and morphometry in cervical condyloma and intraepithelial neoplasia.Int. J. Gynecol. Pathol., 7, 297 (1988).

    Article  PubMed  CAS  Google Scholar 

  6. Furgyik, S., Åstedt, B.: Gonorrheal infection followed by an increased frequency of cervical carcinoma.Acta Obstet. Gynecol. Scand. 59, 521 (1980).

    Article  PubMed  CAS  Google Scholar 

  7. Furgyik, S.: Increased frequency of carcinoma of the uterine cervix in women married to men with a previous gonorrheal infection.Acta Obstet. Gynecol. Scand., 64, 245 (1985).

    PubMed  CAS  Google Scholar 

  8. Furgyik, S.: Die Gonorrhö-Infektion als Risikoindikator für das Kollumkarzinom.Geburtshilf. Frauenheilkd., 47, 320 (1987).

    Article  CAS  Google Scholar 

  9. Hakama, M., Louhivuori, K.: Is there today an epidemic outbreak of cancer of the uterine cervix? In: De Palo, G., Rilke, F., Zur Hausen, H. (eds): Herpes and Papilloma Viruses. Their Role in the Carcinogenesis of the Lower Genital Tract. Vol 46, p. 91. Raven Press, New York 1988.

    Google Scholar 

  10. Howley, P. M.: General and molecular biology of papilloma viruses. In: De Palo G., Rilke, P., Zur Hausen H. (eds.): Herpes and Papilloma Viruses. Their Role in the Carcinogenesis of the Lower Genital Tract. Vol. 46, p. 41. Raven Press, New York 1988.

    Google Scholar 

  11. Josey, W. E., Nahmias, A. J., Naib, M.: Viruses and cancer of the lower genital tract.Cancer, 38, 526 (1976).

    Article  PubMed  CAS  Google Scholar 

  12. Kessler, I.: Human cervical cancer as a venereal disease.Cancer Res., 36, 783 (1976).

    PubMed  CAS  Google Scholar 

  13. Martinez, I.: Relationship of squamous cell carcinoma of the cervix among Puerto Rican women married to men with penile carcinoma.Cancer, 24, 777 (1969).

    Article  PubMed  CAS  Google Scholar 

  14. Meijer, C. J. L. M., Calame, J. J., De Windt, E. J. G., Risse, E. K. J., Bleker, O. P., Kenemans, P., Quint, W. G. V., Meddens, M. J. M.: Prevalence of Chlamydia trachomatis infection in a population of asymptomatic women in a screening program for cervical cancer.Eur. J. Clin. Microbiol. Infect. Dis., 8, 127 (1989).

    Article  PubMed  CAS  Google Scholar 

  15. Munoz, N., Bosch, F. X.: Epidemiological studies implicating human papillomavirus in the causation of carcinoma of the lower genital tract. In: De Palo, G., Rilke, F., Zur Hausen, H. (eds): Herpes and Papilloma Viruses. Their Role in the Carcinogenesis of the Lower Genital Tract. Vol. 46, p. 97. Raven Press, New York 1988.

    Google Scholar 

  16. Ostrow, R. S., Shaver, M. K., Turnquist, S., Viksnins, A., Bender, M., Vance, C., Kaye, V., Faras, A. J.: Human papillomavirus-16DNA in a cutaneous invasive cancer.Arch. Dermatol., 125, 666 (1989).

    Article  PubMed  CAS  Google Scholar 

  17. Péč, J., Kliment, J., Péč, J. Sen, Ľupták, J.: Problems of spinocellular carcinoma of the penis from the aspect of the dermatovenerologist.Cs. Derm., 64, 33 (1989).

    Google Scholar 

  18. Smith, P. G., Kinley, L. F., White, G. C.: Mortality of wives of men dying with cancer of the penis.Br. J. Cancer., 41, 422 (1980).

    PubMed  CAS  Google Scholar 

  19. Swinger, A., Reid, B. L., Coppleson, M.: A hypothesis: The role of the high risk male in the etiology of cervical cancer.Am. J. Obstet. Gynecol., 126, 110 (1976).

    Google Scholar 

  20. Syrjanen, K., Syrjanen, S.: Morphological relationship of papillomavirus infection to cervical vulvar and penile cancer. In: De Palo G., Rilke, F., Zur Hausen H. (eds): Herpes and Papilloma Viruses. Their Role in the Carcinogenesis of the Lower Genital Tract. Vol. 46, p. 179. Raven Press, New York 1988.

    Google Scholar 

  21. Wade, T. R., Kopf, A. W., Ackerman, A. B.: Bowenoid papulosis of the penis.Cancer, 42, 1890 (1978).

    Article  PubMed  CAS  Google Scholar 

  22. Zunzunegui, M. V., King, M. C., Coria, C. F., Charlet, J.: Male influences on cervical cancer risk.Am. J. Epidemiol., 123, 302 (1986).

    PubMed  CAS  Google Scholar 

  23. Zur Hausen, H.: Papillomaviruses in human genital cancer.Med. Oncol. Tumor Pharmacother., 4, 187 (1987).

    PubMed  CAS  Google Scholar 

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Péč, J., Péčová, K., Sen, J.P. et al. A study of possible causal relations between squamous cell carcinoma of the penis and carcinoma of the cervix uteri. International Urology and Nephrology 24, 313–317 (1992). https://doi.org/10.1007/BF02549541

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