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Determination of power—time curves of bacterial growth and study of optimum allowable concentration of a synthetic medicine

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Abstract

The power-time curves ofS. flexneri 6,S. flexneri 3b,S. dysenteae andE. coli were determined by using the 2277 Thermal Activity Monitor (Sweden). From these curves, by using a microorganism growth experimental model with inhibitory conditions, the growth rate constant (μ) was determined at different medicinal concentrations, with the optimum allowable concentration of the synthetic medicine.

Zusammenfassung

Mittels eines Thermal Activity Monitor 2277 (Schweden) wurden die Potenz-Zeit-Kurven vonS. flexneri 6, S. flexneri 3b, S. dysenteae undE. coli ermittelt. Anhand dieser Kurven wurde unter Anwendung eines experimentellen Modells für das Wachstum von Mikroorganismen unter Inhibitorbedingungen die Wachstumsgeschwindigkeitskonstante (μ) bei verschiedenen Arzneimittelkonzentrationen und in Ableitung davon die optimal erreichbare Konzentration des synthetischen Arzneimittels bestimmt.

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References

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Authors and Affiliations

  1. Department of Chemistry, Qufu Normal University, 273165, Qufu Shandong

    Honglin Zhang, Haitao Sun, Yongjun Liu & Zhaodong Nan

  2. Shandong Medical Science University, 250012, Shandong

    Lijun Xu

  3. Qufu Municipal Sanitation and Antiepidemic Station, 273100, Qufu, Shandong

    Qingzhu Shan & Xuofang Su

  4. Department of Chemistry, North-western University, 710069, Xian, P. R. China

    Guoding Zhang

Authors
  1. Honglin Zhang
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  2. Haitao Sun
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  3. Yongjun Liu
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  4. Zhaodong Nan
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  5. Lijun Xu
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  6. Qingzhu Shan
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  7. Xuofang Su
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  8. Guoding Zhang
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Zhang, H., Sun, H., Liu, Y. et al. Determination of power—time curves of bacterial growth and study of optimum allowable concentration of a synthetic medicine. Journal of Thermal Analysis 45, 87–92 (1995). https://doi.org/10.1007/BF02548667

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  • DOI: https://doi.org/10.1007/BF02548667

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