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Thermal analysis in the quality control and standardization of some drugs

  • Pharmaceutical & Organic Compounds
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Abstract

DSC was used together with other methods of pharmaceutical analysis (spectrophotometry, thin-layer chromatography) to estimate the quality and standardization of two drugs—lipoic acid (polymerization upon melting, purity) and progesterone (melting temperature, polymorphism).

Zusammenfassung

Gemeinsam mit anderen Methoden der pharmazeutischen Analyse (Spektrofotometrie, TLC) wurde DSC zur Abschätzung der Güte und Normierung von zwei Wirkstoffen eingesetzt: Liponsäure (Polymerisierung beim Schmelzen, Reinheit) und Progesteron (Schmelz-temperatur, Polymorphie).

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Authors and Affiliations

  1. All-Russian Scientific Institute for vitamin Research, Nauchny Proezd, 14A, GSP-7, 117820, Moscow, Russia

    M. Sh. Lvova, E. I. Kozlov & I. A. Wishnevezkaya

Authors
  1. M. Sh. Lvova
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  2. E. I. Kozlov
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  3. I. A. Wishnevezkaya
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Lvova, M.S., Kozlov, E.I. & Wishnevezkaya, I.A. Thermal analysis in the quality control and standardization of some drugs. Journal of Thermal Analysis 40, 405–411 (1993). https://doi.org/10.1007/BF02546608

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  • DOI: https://doi.org/10.1007/BF02546608

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