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The reiter protein complement fixation test in experimental syphilis

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Summary

The pattern of the antibody reacting in the Reiter protein complement fixation (RPCF) test was studied in experimental syphilis of the rabbit in comparison with the patterns of reagin and immobilisin. In accordance with the data on syphilitic patients it was found that the RP antibody appears in the rabbit sera after reagin but before or simultaneous with immobilisin.

After treatment reagin is the first to disappear, followed by the immobilizing antibody and later by the RP antibody. Like immobilisin the duration of the occurrence of the RP antibody in the serum depends on the stage of the disease at which treatment was given. The more time elapses between infection and treatment the longer the RPCF test remains positive.

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Authors and Affiliations

  1. Laboratory of Bacteriology and Serology, National Institute of Public Health, Utrecht, Netherlands

    J. H. Bekker & P. C. Onvlee

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  1. J. H. Bekker
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  2. P. C. Onvlee
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Bekker, J.H., Onvlee, P.C. The reiter protein complement fixation test in experimental syphilis. Antonie van Leeuwenhoek 25, 38–40 (1959). https://doi.org/10.1007/BF02542829

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  • DOI: https://doi.org/10.1007/BF02542829

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